The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
In Vitro Corrosion and Cytocompatibility of a Microarc Oxidation Coating and Poly(l-lactic acid) Composite Coating on Mg–1Li–1Ca Alloy for Orthopedic Implants
Abstract
Manipulating the degradation rate of biomedical magnesium alloys poses a challenge. The characteristics of a microarc oxidation (MAO), prepared in phytic acid, and poly(L-lactic acid) (PLLA) composite coating, fabricated on a novel Mg-1Li-1Ca alloy, were studied through field emission scanning electron microscopy (FE-SEM), electron probe X-ray microanalysis (EPMA), energy dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). The corrosion behaviors of the samples were evaluated via hydrogen evolution, potentiodynamic polarization and electrochemical impedance spectroscopy in Hanks' solution. The results indicated that the MAO/PLLA composite coatings significantly enhanced the corrosion resistance of the Mg-1Li-1Ca alloy. MTT and ALP assays using MC3T3 osteoblasts indicated that the MAO/PLLA coatings greatly improved the cytocompatibility, and the morphology of the cells cultured on different samples exhibited good adhesion. Hemolysis tests showed that the composite coatings endowed the Mg-1Li-1Ca alloys with a low hemolysis ratio. The increased solution pH resulting from the corrosion of magnesium could be tailored by the degradation of PLLA. The degradation mechanism of the composite coatings was discussed. The MAO/PLLA composite coating may be appropriate for applications on degradable Mg-based orthopedic implants.
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Cites
A Literature Review of Poly(Lactic Acid)
Garlotta, D. (2001) · Journal of Polymers and the Environment · doi:10.1023/a:1020200822435 · Cited by 3,707
Biodegradation and biocompatibility of PLA and PLGA microspheres
Anderson, J. M., & Shive, M. S. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00048-3 · Cited by 2,617
Cited by
Advances in functionalized polymer coatings on biodegradable magnesium alloys–A review
Li, L.-Y., Cui, L.-Y., Zeng, R.-C., Li, S.-Q., Chen, X.-B., Zheng, Y., & Kannan, M. B. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.08.030 · Cited by 466
Self-citationCui, L.-Y., Gao, S.-D., Li, P.-P., Zeng, R.-C., Zhang, F., Li, S.-Q., & Han, E.-H. (2017) · Corrosion Science · doi:10.1016/j.corsci.2017.01.025 · Cited by 425
Self-citationBiodegradable magnesium‐based biomaterials: An overview of challenges and opportunities
Amukarimi, S., & Mozafari, M. (2021) · MedComm · doi:10.1002/mco2.59 · Cited by 258
A review on magnesium alloys for biomedical applications
Zhang, T., Wang, W., Liu, J., Wang, L., Tang, Y., & Wang, K. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.953344 · Cited by 208
Zou, Y.-H., Wang, J., Cui, L.-Y., Zeng, R.-C., Wang, Q.-Z., Han, Q.-X., Qiu, J., Chen, X.-B., Chen, D.-C., Guan, S.-K., et al. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.05.069 · Cited by 173
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Metadata
- Authors
- Zeng, R.-C., Cui, L.-Y., Jiang, K., Liu, R., Zhao, B.-D., & Zheng, Y.-F.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-04-05
- Volume
- 8
- Issue
- 15
- Pages
- 10014-10028
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2332268599
- Cited by
- 314
- References
- 2
- FWCI
- 12.91
- Type
- journal article
- Language
- en
- Open access
- closed
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