The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Phosphorus and Nitrogen Dual-Doped Hollow Carbon Dot as a Nanocarrier for Doxorubicin Delivery and Biological Imaging
Abstract
Innovative phosphorus and nitrogen dual-doped hollow carbon dots (PNHCDs) have been fabricated for anticancer drug delivery and biological imaging. The functional groups of PNHCDs are introduced by simply mixing glucose, 1,2-ethylenediamine, and concentrated phosphoric acid. This is an automatic method without external heat treatment to rapidly produce large quantities of PNHCDs, which avoid high temperature, complicated operations, and long reaction times. The as-prepared PNHCDs possess small particle size, hollow structure, and abundant phosphate/hydroxyl/pyridinic/pyrrolic-like N groups, endowing PNHCDs with fluorescent properties, improving the accuracy of PNHCDs as an optical monitoring code both in vitro and in vivo. The investigation of PNHCDs as an anticancer drug nanocarrier for doxorubicin (DOX) indicates a better antitumor efficacy than free DOX owing to its enhanced nuclear delivery in vitro and tumor accumulation in vivo, which results in highly effective tumor growth inhibition and improved targeted therapy for cancer in clinical medicine.
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Cho, H.-S., Dong, Z., Pauletti, G. M., Zhang, J., Xu, H., Gu, H., Wang, L., Ewing, R. C., Huth, C., Wang, F., et al. (2010) · ACS Nano · doi:10.1021/nn101000e · Cited by 265
Cited by
Jiang, K., Wang, Y., Gao, X., Cai, C., & Lin, H. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201802441 · Cited by 630
Jiang, K., Wang, Y., Cai, C., & Lin, H. (2018) · Advanced Materials · doi:10.1002/adma.201800783 · Cited by 586
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery
Panwar, N., Soehartono, A. M., Chan, K. K., Zeng, S., Xu, G., Qu, J., Coquet, P., Yong, K.-T., & Chen, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00099 · Cited by 555
Carbon Dot-Based Platform for Simultaneous Bacterial Distinguishment and Antibacterial Applications
Yang, J., Zhang, X., Ma, Y.-H., Gao, G., Chen, X., Jia, H.-R., Li, Y.-H., Chen, Z., & Wu, F.-G. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b10398 · Cited by 409
Recent advances in carbon dots for bioimaging applications
Li, H., Yan, X., Kong, D., Jin, R., Sun, C., Du, D., Lin, Y., & Lu, G. (2020) · Nanoscale Horizons · doi:10.1039/c9nh00476a · Cited by 304
Metadata
- Authors
- Gong, X., Zhang, Q., Gao, Y., Shuang, S., Choi, M. M. F., & Dong, C.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-04-26
- Volume
- 8
- Issue
- 18
- Pages
- 11288-11297
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2341212733
- Cited by
- 311
- References
- 1
- FWCI
- 16.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gong, X., Zhang, Q., Gao, Y., Shuang, S., Choi, M. M. F., & Dong, C. (2016). Phosphorus and Nitrogen Dual-Doped Hollow Carbon Dot as a Nanocarrier for Doxorubicin Delivery and Biological Imaging. ACS Applied Materials & Interfaces. https://doi.org/10.1021/acsami.6b01577
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