The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Reversal of Regioselectivity in Ynamide Chemistry
Abstract
Ynamides are special alkynes bearing an electron-withdrawing group on the nitrogen atom, and they have been extensively studied over the past decade. However, the addition of functional groups across ynamides in these transformations typically occurs at the α-position of the ynamide because of the strong polarization of the alkynyl moiety. Studies of umpolung transformations in ynamide chemistry may not only discover organic reactions but also lead to divergent organic syntheses, thus significantly enriching ynamide chemistry. This review summarizes four main strategies utilized to achieve reversal of the regioselectivity, including the ring strain factor, metal–carbonyl (or sulfonyl) chelation, and base-mediated and radical-initiated addition.
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Cites
Ynamides: A Modern Functional Group for the New Millennium
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Ynamides in Ring Forming Transformations
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Self-citationYnamides as Racemization-Free Coupling Reagents for Amide and Peptide Synthesis
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Stereodivergent synthesis of 1,4-dicarbonyls by traceless charge–accelerated sulfonium rearrangement
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A unique approach to aldol products for the creation of all-carbon quaternary stereocentres
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Synthesis of Functionalized Oxazolones by a Sequence of Cu(II)- and Au(I)-Catalyzed Transformations
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Cited by
Ynamide-Mediated Thionoester and Dithioester Syntheses
Yao, C., Yang, J., Lu, X., Zhang, S., & Zhao, J. (2020) · Organic Letters · doi:10.1021/acs.orglett.0c02402 · Cited by 35
Metadata
- Authors
- Zhou, B., Tan, T.-D., Zhu, X.-Q., Shang, M., & Ye, L.-W.
- Venue
- ACS Catalysis
- Publisher
- American Chemical Society (ACS)
- Published
- 2019-06-05
- Volume
- 9
- Issue
- 7
- Pages
- 6393-6406
- ISSN
- 2155-5435 (ISSN-L)
- OpenAlex
- W2948495562
- Cited by
- 294
- References
- 32
- FWCI
- 15.12
- Type
- journal article
- Language
- en
- Open access
- closed
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