The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Copper-Catalyzed Oxidative Diamination of Terminal Alkynes by Amidines: Synthesis of 1,2,4-Trisubstituted Imidazoles
Abstract
An efficient copper-catalyzed synthesis of 1,2,4-trisubstituted imidazoles using amidines and terminal alkynes has been developed. Overall, the oxidative process, which involves Na2CO3, pyridine, a catalytic amount of CuCl2·2H2O, and oxygen (1 atm), consisted of a regioselective diamination of alkynes allowing the synthesis of diverse imidazoles in modest to good yields.
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Cites
Topics in Current Chemistry: Inorganic Biochemistry
(1976) · Topics in Current Chemistry · doi:10.1007/bfb0045697 · Cited by 1,044
Cited by
Ynamides in Ring Forming Transformations
Wang, X.-N., Yeom, H.-S., Fang, L.-C., He, S., Ma, Z.-X., Kedrowski, B. L., & Hsung, R. P. (2014) · Accounts of Chemical Research · doi:10.1021/ar400193g · Cited by 605
Reversal of Regioselectivity in Ynamide Chemistry
Zhou, B., Tan, T.-D., Zhu, X.-Q., Shang, M., & Ye, L.-W. (2019) · ACS Catalysis · doi:10.1021/acscatal.9b01851 · Cited by 294
Metadata
- Authors
- Li, J., & Neuville, L.
- Venue
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-03-25
- Volume
- 15
- Issue
- 7
- Pages
- 1752-1755
- ISSN
- 1523-7052 (ISSN-L)
- 1523-7060
- OpenAlex
- W2334412483
- Cited by
- 160
- References
- 1
- FWCI
- 11.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Copper-Catalyzed Oxidative Diamination of Terminal Alkynes by Amidines: Synthesis of 1,2,4-Trisubstituted Imidazoles. https://app.cochat.ai/papers/10.1021/ol400560m
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- Li, J., & Neuville, L. (2013). Copper-Catalyzed Oxidative Diamination of Terminal Alkynes by Amidines: Synthesis of 1,2,4-Trisubstituted Imidazoles. Organic Letters. https://doi.org/10.1021/ol400560m
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