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Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method

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Horn, Evan J., Rosen, Brandon R., Baran, Phil S.·2016·ACS Central Science

Abstract

While preparative electrolysis of organic molecules has been an active area of research over the past century, modern synthetic chemists have generally been reluctant to adopt this technology. In fact, electrochemical methods possess many benefits over traditional reagent-based transformations, such as high functional group tolerance, mild conditions, and innate scalability and sustainability. In this Outlook we highlight illustrative examples of electrochemical reactions in the context of the synthesis of complex molecules, showcasing the intrinsic benefits of electrochemical reactions versus traditional reagent-based approaches. Our hope is that this field will soon see widespread adoption in the synthetic community.

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Metadata

Authors
Horn, E. J., Rosen, B. R., & Baran, P. S.
Venue
ACS Central Science
Published
2016-05-05
Volume
2
Issue
5
Pages
302-308
ISSN
  • 2374-7943 (ISSN-L)
  • 2374-7951
OpenAlex
W2347015396
Cited by
1,068
References
1
FWCI
50.78
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method. https://app.cochat.ai/papers/10.1021/acscentsci.6b00091
The paper
Horn, E. J., Rosen, B. R., & Baran, P. S. (2016). Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method. ACS Central Science. https://doi.org/10.1021/acscentsci.6b00091

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.