Novel histone acetyltransferase (HAT) inhibitors for treating diseases
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ADVERTISEMENT RETURN TO ISSUEPREVPatent HighlightNEXTNovel Histone Acetyltransferase (HAT) Inhibitors for Treating DiseasesRam W. Sabnis*Ram W. SabnisSmith, Gambrell & Russell LLP, 1230 Peachtree Street NE, Suite 3100, Atlanta, Georgia 30309, United States*Email: [email protected]More by Ram W. Sabnishttps://orcid.org/0000-0001-7289-0581Cite this: ACS Med. Chem. Lett. 2021, 12, 8, 1198–1199Publication Date (Web):July 1, 2021Publication History Received14 June 2021Published online1 July 2021Published inissue 12 August 2021https://doi.org/10.1021/acsmedchemlett.1c00337Copyright © Published 2021 by American Chemical SocietyRIGHTS & PERMISSIONSArticle Views786Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (767 KB) Get e-AlertsSUBJECTS:Peptides and proteins,Genetics,Monomers,Inhibitors,Alkyls Get e-Alerts
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Current development of CBP/p300 inhibitors in the last decade
He, Z., Wei, B., Zhang, X., Gong, Y., Ma, L., & Zhao, W. H. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112861 · Cited by 140 · see citing works
Cognitive epigenetic priming: leveraging histone acetylation for memory amelioration
Burns, A. M., & Gräff, J. (2021) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.08.011 · Cited by 62 · see citing works
Targeting histone acetylation/deacetylation in parasites: an update (2017–2020)
Fioravanti, R., Mautone, N., Rovere, A., Rotili, D., & Mai, A. (2020) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2020.05.008 · Cited by 61 · see citing works
Wang, Y., Xie, Q., Tan, H., Liao, M., Zhu, S., Zheng, L., Huang, H., & Liu, B. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105702 · Cited by 41 · see citing works
Histone acetyl transferases and their epigenetic impact on bone remodeling
Gomathi, K., Akshaya, N., Srinaath, N., Rohini, M., & Selvamurugan, N. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.12.173 · Cited by 24 · see citing works
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Research works printed but not linked: 5
- He Z.; Wei B.; Zhang X.; Gong Y.; Ma L.; Zhao W.. Eur. J. Med. Chem. 2021, 209, 112861.
- Gomathi K.; Akshaya N.; Srinaath N.; Rohini M.; Selvamurugan N.. Int. J. Biol. Macromol. 2021, 170, 326.
- Wang Y.; Xie Q.; Tan H.; Liao M.; Zhu S.; Zheng L.; Huang H.; Liu B.. Pharmacol. Res. 2021, in press.
- Burns A. M.; Graff J.. Curr. Opin. Neurobiol. 2021, 67, 75.
- Fioravanti R.; Mautone N.; Rovere A.; Rotili D.; Mai A.. Curr. Opin. Chem. Biol. 2020, 57, 65.
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Acetylation of histone H3 in cancer progression and prognosis
Miziak, P., Baran, M., Borkiewicz, L., Trombik, T., & Stepulak, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252010982 · Cited by 49 · see citing works
Lv, L.-Z., Wang, Z.-D., Ren, J.-J., Li, L.-H., Liu, X.-B., Li, J.-L., Zhu, H., Jiang, B., Han, Y.-P., Zhou, X.-M., et al. (2026) · Frontiers in Genetics · doi:10.3389/fgene.2025.1722453 · Cited by 7 · see citing works
“Major HAT families include GNAT, p300/CBP, MYST, and Rtt109 (Poziello et al., 2021; Sabnis, 2021; Di Cerbo and Schneider, 2013).”
- Authors
- Sabnis, R. W.
- Affiliations
- Smith, Gambrell & Russell LLP, 1230 Peachtree Street NE, Suite 3100, Atlanta, Georgia 30309, United States
- Corresponding author
- Sabnis, Ram W.
- ORCID
- Sabnis, Ram W.
- Venue
- ACS Medicinal Chemistry Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2021-07-01
- Volume
- 12
- Issue
- 8
- Pages
- 1198-1199
- ISSN
- 1948-5875 (ISSN-L)
- PMC
- PMC8365625
- OpenAlex
- W3194407496
- Cited by
- 17
- References
- 5
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 6 · 2023: 1 · 2022: 8
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- ACS Medicinal Chemistry Letters (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Histone Deacetylase Inhibitors Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Keywords
- histone acetyltransferase inhibitors, epigenetic drug discovery, histone acetylation, disease treatment
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