The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Exudate Absorbing and Antimicrobial Hydrogel Integrated with Multifunctional Curcumin-Loaded Magnesium Polyphenol Network for Facilitating Burn Wound Healing
Abstract
Burns are among the most common causes of trauma worldwide. Reducing the healing time of deep burn wounds has always been a major challenge. Traditional dressings not only require a lengthy medical procedure but also cause unbearable pain and secondary damage to patients. In this study, we developed an exudate-absorbing and antimicrobial hydrogel with a curcumin-loaded magnesium polyphenol network (Cur-Mg@PP) to promote burn wound healing. That hydrogel was composed of an ε-poly- l -lysine (ε-PLL)/polymer poly(γ-glutamic acid) (γ-PGA) hydrogel (PP) and curcumin-loaded magnesium polyphenol network (Cur-Mg). Because of the strong water absorption property of ε-PLL and γ-PGA, Cur-Mg@PP powder can quickly absorb the wound exudate and transform into a moist and viscous hydrogel, thus releasing payloads such as magnesium ion (Mg 2+ ) and curcumin (Cur). The released Mg 2+ and Cur demonstrated good therapeutic efficacy on analgesic, antioxidant, anti-inflammation, angiogenesis, and tissue regeneration. Our findings provide a strategy for accelerating burn wound healing.
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1 retracted
Babaluei, M., Mottaghitalab, F., Seifalian, A. M., & Farokhi, M. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124005 · Cited by 45
RetractedChronic pain: an update on burden, best practices, and new advances
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Jeschke, M. G., van Baar, M. E., Choudhry, M. A., Chung, K. K., Gibran, N. S., & Logsetty, S. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0145-5 · Cited by 1,664
Coding of facial expressions of pain in the laboratory mouse
Langford, D. J., Bailey, A. L., Chanda, M. L., Clarke, S. E., Drummond, T. E., Echols, S., Glick, S., Ingrao, J., Klassen-Ross, T., LaCroix-Fralish, M. L., et al. (2010) · Nature Methods · doi:10.1038/nmeth.1455 · Cited by 1,489
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Burn injury: Challenges and advances in burn wound healing, infection, pain and scarring
Wang, Y., Beekman, J., Hew, J., Jackson, S., Issler-Fisher, A. C., Parungao, R., Lajevardi, S. S., Li, Z., & Maitz, P. K. M. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.09.018 · Cited by 696
Cellular and molecular mechanisms of curcumin in prevention and treatment of disease
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Yin, M., Wu, J., Deng, M., Wang, P., Ji, G., Wang, M., Zhou, C., Blum, N. T., Zhang, W., Shi, H., et al. (2021) · ACS Nano · doi:10.1021/acsnano.1c06036 · Cited by 380
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Cited by
Wang, Y., Yang, C., Zhang, W., Wang, X., Zhao, Z., Wang, Z., & Zhang, L. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.140326 · Cited by 27
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Metadata
- Authors
- Gong, Y., Wang, P., Cao, R., Wu, J., Ji, H., Wang, M., Hu, C., Huang, P., & Wang, X.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2023-11-06
- Volume
- 17
- Issue
- 22
- Pages
- 22355-22370
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W4388423539
- Cited by
- 291
- References
- 38
- FWCI
- 27.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gong, Y., Wang, P., Cao, R., Wu, J., Ji, H., Wang, M., Hu, C., Huang, P., & Wang, X. (2023). Exudate Absorbing and Antimicrobial Hydrogel Integrated with Multifunctional Curcumin-Loaded Magnesium Polyphenol Network for Facilitating Burn Wound Healing. ACS Nano. https://doi.org/10.1021/acsnano.3c04556
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