The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Ultrasensitive Profiling of Metabolites Using Tyramine-Functionalized Graphene Quantum Dots
Open accessAbstract
Graphene quantum dots (GQDs) are emerging fluorescence reporters attractive for optical sensing, owing to their high photostability, highly tunable photoluminescence, molecular size, atomically thin structure, biocompatibility, and ease of functionalization. Herein, we present a fluorometric sensing platform based on tyramine-functionalized GQDs, which is able to detect a spectrum of metabolites with high sensitivity and specificity. Furthermore, multiparametric blood analysis (glucose, cholesterol, L-lactate, and xanthine) is demonstrated. This convenient metabolite profiling technique could be instrumental for diagnosis, study, and management of metabolic disorders and associated diseases, such as diabetes, obesity, lactic acidosis, gout, and hypertension.
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Citations
Cites
Glowing Graphene Quantum Dots and Carbon Dots: Properties, Syntheses, and Biological Applications
Zheng, X. T., Ananthanarayanan, A., Luo, K. Q., & Chen, P. (2015) · Small · doi:10.1002/smll.201402648 · Cited by 2,190
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Cited by
A review on graphene-based nanocomposites for electrochemical and fluorescent biosensors
Krishnan, S. K., Singh, E., Singh, P., Meyyappan, M., & Nalwa, H. S. (2019) · RSC Advances · doi:10.1039/c8ra09577a · Cited by 785
pH-Sensitive ZnO Quantum Dots–Doxorubicin Nanoparticles for Lung Cancer Targeted Drug Delivery
Cai, X., Luo, Y., Zhang, W., Du, D., & Lin, Y. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b04933 · Cited by 359
Graphene-based nano composites and their applications. A review
Lawal, A. T. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.111384 · Cited by 344
Fluorescent carbon dots functionalization
Chen, B. B., Liu, M. L., Li, C. M., & Huang, C. Z. (2019) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2019.06.008 · Cited by 344
Photonic Carbon Dots as an Emerging Nanoagent for Biomedical and Healthcare Applications
Chung, Y. J., Kim, J., & Park, C. B. (2020) · ACS Nano · doi:10.1021/acsnano.0c02114 · Cited by 299
Metadata
- Authors
- Li, N., Than, A., Wang, X., Xu, S., Sun, L., Duan, H., Xu, C., & Chen, P.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-03-03
- Volume
- 10
- Issue
- 3
- Pages
- 3622-3629
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2290971389
- Cited by
- 170
- References
- 1
- FWCI
- 11.21
- Type
- journal article
- Language
- en
- Open access
- green
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