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Cited by 337

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions

Open access
Anchordoquy, Thomas J., Barenholz, Yechezkel, Boraschi, Diana, Chorny, Michael, Decuzzi, Paolo, Dobrovolskaia, Marina A., Farhangrazi, Z. Shadi, Farrell, Dorothy, Gabizon, Alberto, Ghandehari, Hamidreza, Godin, Biana, La-Beck, Ninh M., Ljubimova, Julia, Moghimi, S. Moein, Pagliaro, Len, Park, Ji-Ho, Peer, Dan, Ruoslahti, Erkki, Serkova, Natalie J., Simberg, Dmitri·2017·ACS Nano

Abstract

Remarkable progress has recently been made in the synthesis and characterization of engineered nanoparticles for imaging and treatment of cancers, resulting in several promising candidates in clinical trials. Despite these advances, clinical applications of nanoparticle-based therapeutic/imaging agents remain limited by biological, immunological, and translational barriers. In order to overcome the existing status quo in drug delivery, there is a need for open and frank discussion in the nanomedicine community on what is needed to make qualitative leaps toward translation. In this Nano Focus, we present the main discussion topics and conclusions from a recent workshop: "Mechanisms and Barriers in Nanomedicine". The focus of this informal meeting was on biological, toxicological, immunological, and translational aspects of nanomedicine and approaches to move the field forward productively. We believe that these topics reflect the most important issues in cancer nanomedicine.

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Crossref · 10.1021/acsnano.6b08244

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Metadata

Authors
Anchordoquy, T. J., Barenholz, Y., Boraschi, D., Chorny, M., Decuzzi, P., Dobrovolskaia, M. A., Farhangrazi, Z. S., Farrell, D., Gabizon, A., Ghandehari, H., Godin, B., La-Beck, N. M., Ljubimova, J., Moghimi, S. M., Pagliaro, L., Park, J.-H., Peer, D., Ruoslahti, E., Serkova, N. J., & Simberg, D.
Venue
ACS Nano
Published
2017-01-09
Volume
11
Issue
1
Pages
12-18
ISSN
  • 1936-0851 (ISSN-L)
  • 1936-086X
OpenAlex
W2568972635
Cited by
337
References
2
Type
other
Language
en
Open access
green

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