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Surface Modification of Lipid-Based Nanocarriers: A Potential Approach to Enhance Targeted Drug Delivery

Priya, Sakshi, Desai, Vaibhavi Meghraj, Singhvi, Gautam·2023·ACS Omega
DOI 10.1021/acsomega.2c05976PMC PMC9835629
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Figure 1 Diagrammatic representation of different types of surface modifiers used for modification of the surface of lipid-based nanocarriers.
Figure 1 Diagrammatic representation of different types of surface modifiers used for modification of the surface of lipid-based nanocarriers.CC BY-NC-ND · PubMed Central
Figure 2 Schematic illustration of the effect of surface modification on the performance of the lipid nanocarrier system.
Figure 2 Schematic illustration of the effect of surface modification on the performance of the lipid nanocarrier system.CC BY-NC-ND · PubMed Central
Figure 3 (a) Schematic illustration of preparation and application of PTX-CTs/Gel as a paintable patch for topical drug delivery. (b) Schematic illustration of enhancement on the transdermal efficiency of PTX by the PTX-CTs/Gel for noninvasive chemotherapy of melanoma. Adapted from ref (25). Copyright 2018 American Chemical Society.
Figure 3 (a) Schematic illustration of preparation and application of PTX-CTs/Gel as a paintable patch for topical drug delivery. (b) Schematic illustration of enhancement on the transdermal efficiency of PTX by the PTX-CTs/Gel for noninvasive chemotherapy of melanoma. Adapted from ref (25). Copyright 2018 American Chemical Society.CC BY-NC-ND · PubMed Central
Figure 4 Graphical representation of TF and TF-FA cellular uptake by (A) U-87 MG and (B) L929 cells. Two-way ANOVA followed by Tukey post-test (p < 0.05) (n = 3). Adapted with permission from ref (52). Copyright 2021 Elsevier.
Figure 4 Graphical representation of TF and TF-FA cellular uptake by (A) U-87 MG and (B) L929 cells. Two-way ANOVA followed by Tukey post-test (p < 0.05) (n = 3). Adapted with permission from ref (52). Copyright 2021 Elsevier.CC BY-NC-ND · PubMed Central
Figure 5 (a) Mechanism of anticancer activity of HA-IM-CBs. (b) After orally administering IM, IM-CBs, and HA-IM-CBs in rats, plasma drug concentrations were measured at different time intervals. Adapted with permission from ref (57). Copyright 2022 Elsevier.
Figure 5 (a) Mechanism of anticancer activity of HA-IM-CBs. (b) After orally administering IM, IM-CBs, and HA-IM-CBs in rats, plasma drug concentrations were measured at different time intervals. Adapted with permission from ref (57). Copyright 2022 Elsevier.CC BY-NC-ND · PubMed Central

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Metadata

Authors
Priya, S., Desai, V. M., & Singhvi, G.
Affiliations
Industrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science (BITS) - Pilani, Pilani Campus, Pilani, Rajasthan 333031, India
ORCID
Singhvi, Gautam
Venue
ACS Omega
Publisher
American Chemical Society (ACS)
Published
2022-12-20
Volume
8
Issue
1
Pages
74-86
ISSN
2470-1343
DOI
10.1021/acsomega.2c05976
PMC
PMC9835629
Cited by
228
References
1
Language
en
Licence
creativecommons.org/licenses/by-nc-nd/4.0/ (unspecified)

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