The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
Advancing Biosensors with Machine Learning
Abstract
Chemometrics play a critical role in biosensors-based detection, analysis, and diagnosis. Nowadays, as a branch of artificial intelligence (AI), machine learning (ML) have achieved impressive advances. However, novel advanced ML methods, especially deep learning, which is famous for image analysis, facial recognition, and speech recognition, has remained relatively elusive to the biosensor community. Herein, how ML can be beneficial to biosensors is systematically discussed. The advantages and drawbacks of most popular ML algorithms are summarized on the basis of sensing data analysis. Specially, deep learning methods such as convolutional neural network (CNN) and recurrent neural network (RNN) are emphasized. Diverse ML-assisted electrochemical biosensors, wearable electronics, SERS and other spectra-based biosensors, fluorescence biosensors and colorimetric biosensors are comprehensively discussed. Furthermore, biosensor networks and multibiosensor data fusion are introduced. This review will nicely bridge ML with biosensors, and greatly expand chemometrics for detection, analysis, and diagnosis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hochreiter, S., & Schmidhuber, J. (1997) · Neural Computation · doi:10.1162/neco.1997.9.8.1735 · Cited by 102,318
Going deeper with convolutions
Szegedy, C., Liu, W., Jia, Y., Sermanet, P., Reed, S., Anguelov, D., Erhan, D., Vanhoucke, V., & Rabinovich, A. (2015) · 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr.2015.7298594 · Cited by 48,562
He, K., Gkioxari, G., Dollar, P., & Girshick, R. (2017) · 2017 IEEE International Conference on Computer Vision (ICCV) · doi:10.1109/iccv.2017.322 · Cited by 29,137
Delving Deep into Rectifiers: Surpassing Human-Level Performance on ImageNet Classification
He, K., Zhang, X., Ren, S., & Sun, J. (2015) · 2015 IEEE International Conference on Computer Vision (ICCV) · doi:10.1109/iccv.2015.123 · Cited by 19,741
(2010) · Cited by 14,134
Kim, D.-H., Lu, N., Ma, R., Kim, Y.-S., Kim, R.-H., Wang, S., Wu, J., Won, S. M., Tao, H., Islam, A., et al. (2011) · Science · doi:10.1126/science.1206157 · Cited by 4,836
Self-citationDeep Convolutional and LSTM Recurrent Neural Networks for Multimodal Wearable Activity Recognition
Ordóñez, F., & Roggen, D. (2016) · Sensors · doi:10.3390/s16010115 · Cited by 2,761
Brain Tumor Segmentation Using Convolutional Neural Networks in MRI Images
Pereira, S., Pinto, A., Alves, V., & Silva, C. A. (2016) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2016.2538465 · Cited by 2,735
Peterson, L. (2009) · Scholarpedia · doi:10.4249/scholarpedia.1883 · Cited by 2,433
Skin electronics from scalable fabrication of an intrinsically stretchable transistor array
Wang, S., Xu, J., Wang, W., Wang, G.-J. N., Rastak, R., Molina-Lopez, F., Chung, J. W., Niu, S., Feig, V. R., Lopez, J., et al. (2018) · Nature · doi:10.1038/nature25494 · Cited by 2,198
Research works printed but not linked: 42
- 10.1016/j.bios.2017.11.068 · doi:10.1016/j.bios.2017.11.068
- 10.1021/acsami.6b15077 · doi:10.1021/acsami.6b15077
- 10.1016/j.trac.2019.115668 · doi:10.1016/j.trac.2019.115668
- Weber, P.; Vogler, J.; Gauglitz, G. In Development of an optical biosensor for the detection of antibiotics in the environment, Optical Sensors 2017 ; International Society for Optics and Photonics: 2017; p 102312L. · doi:10.1117/12.2267467
- 10.1016/j.trac.2019.05.014 · doi:10.1016/j.trac.2019.05.014
- 10.1021/acsanm.9b02001 · doi:10.1021/acsanm.9b02001
- 10.3390/s20040996 · doi:10.3390/s20040996
- 10.1016/j.trac.2015.03.006 · doi:10.1016/j.trac.2015.03.006
- Otto M., 2016, Chemometrics: statistics and computer application in analytical chemistry, 10.1002/9783527699377 · doi:10.1002/9783527699377
- 10.1081/AL-120016533 · doi:10.1081/al-120016533
- 10.1007/s00216-010-4027-7 · doi:10.1007/s00216-010-4027-7
- 10.1002/cem.1100 · doi:10.1002/cem.1100
- 10.1016/j.snb.2008.07.009 · doi:10.1016/j.snb.2008.07.009
- 10.1016/j.saa.2019.117380 · doi:10.1016/j.saa.2019.117380
- 10.1016/j.aca.2015.04.011 · doi:10.1016/j.aca.2015.04.011
- 10.1016/j.bios.2016.04.080 · doi:10.1016/j.bios.2016.04.080
- 10.1016/j.snb.2009.12.017 · doi:10.1016/j.snb.2009.12.017
- Dasgupta A., 2016, International Journal of Innovative Research in Advanced Engineering (IJIRAE), 3, 6
- Mitchell R., 2013, An artificial intelligence approach
- Goodfellow I., 2016, Deep learning
- 10.1186/s13036-017-0051-x · doi:10.1186/s13036-017-0051-x
- Islam, M. M.; Iqbal, H.; Haque, M. R.; Hasan, M. K. In Prediction of breast cancer using support vector machine and K-Nearest neighbors ; 2017 IEEE Region 10 Humanitarian Technology Conference (R10-HTC), IEEE: 2017; pp 226–229. · doi:10.1109/r10-htc.2017.8288944
- Si, S.; Zhang, H.; Keerthi, S. S.; Mahajan, D.; Dhillon, I. S.; Hsieh, C.J. In Gradient Boosted Decision Trees for High Dimensional Sparse Output ; International Conference on Machine Learning, 2017; pp 3182–3190.
- 10.1016/j.aca.2020.06.043 · doi:10.1016/j.aca.2020.06.043
- 10.1080/03235408.2013.772321 · doi:10.1080/03235408.2013.772321
- Lee J., 2017, arXiv
- Lipton Z. C., 2015, arXiv
- Williams J. D., 2016, arXiv
- Zoph B., 2016, arXiv
- Peng Y., 2018, arXiv
- 10.1039/C8AN00065D · doi:10.1039/c8an00065d
- 10.1038/s41598-018-24208-2 · doi:10.1038/s41598-018-24208-2
- González-Calabuig A., 2017, High dimensionality voltammetric biosensor data processed with artificial neural networks
- 10.1016/j.aca.2008.08.009 · doi:10.1016/j.aca.2008.08.009
- 10.1021/acsomega.9b03660 · doi:10.1021/acsomega.9b03660
- 10.1021/jacs.8b10854 · doi:10.1021/jacs.8b10854
- 10.1021/acs.analchem.7b04950 · doi:10.1021/acs.analchem.7b04950
- Fan, Q.; Chen, G.; Zhou, X.; Li, L. In Image Threshold Segmentation Based on Auxiliary Individual Oriented Crossover Genetic Algorithm ; 2019 IEEE International Conference on Industrial Internet (ICII), IEEE: 2019; pp 411–416. · doi:10.1109/icii.2019.00076
- 10.3390/bios8030085 · doi:10.3390/bios8030085
- 10.1039/C9AN02267H · doi:10.1039/c9an02267h
- 10.1016/j.snb.2018.05.100 · doi:10.1016/j.snb.2018.05.100
- 10.1016/j.jestch.2019.06.011 · doi:10.1016/j.jestch.2019.06.011
Cited by
End-to-end design of wearable sensors
Ates, H. C., Nguyen, P. Q., Gonzalez-Macia, L., Morales-Narváez, E., Güder, F., Collins, J. J., & Dincer, C. (2022) · Nature Reviews Materials · doi:10.1038/s41578-022-00460-x · Cited by 1,306
Ammara, G., NIE, X., & -hua LIU, C. (2024) · International Journal of Innovative Science and Research Technology (IJISRT) · doi:10.38124/ijisrt/ijisrt24may2382 · Cited by 958
Wearable chemical sensors for biomarker discovery in the omics era
Sempionatto, J. R., Lasalde-Ramírez, J. A., Mahato, K., Wang, J., & Gao, W. (2022) · Nature Reviews Chemistry · doi:10.1038/s41570-022-00439-w · Cited by 613
Hybrid multimodal wearable sensors for comprehensive health monitoring
Mahato, K., Saha, T., Ding, S., Sandhu, S. S., Chang, A.-Y., & Wang, J. (2024) · Nature Electronics · doi:10.1038/s41928-024-01247-4 · Cited by 404
Sun, T., Feng, B., Huo, J., Xiao, Y., Wang, W., Peng, J., Li, Z., Du, C., Wang, W., Zou, G., et al. (2024) · Nano-Micro Letters · doi:10.1007/s40820-023-01235-x · Cited by 384
Metadata
- Authors
- Cui, F., Yue, Y., Zhang, Y., Zhang, Z., & Zhou, H. S.
- Venue
- ACS Sensors
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-11-13
- Volume
- 5
- Issue
- 11
- Pages
- 3346-3364
- ISSN
- 2379-3694 (ISSN-L)
- OpenAlex
- W3100709371
- Cited by
- 768
- References
- 147
- FWCI
- 23.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Funders
- National Science Foundation (CBET-1805514)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Advancing Biosensors with Machine Learning. https://app.cochat.ai/papers/10.1021/acssensors.0c01424
- The paper
- Cui, F., Yue, Y., Zhang, Y., Zhang, Z., & Zhou, H. S. (2020). Advancing Biosensors with Machine Learning. ACS Sensors. https://doi.org/10.1021/acssensors.0c01424
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.