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Facile, One-Pot Synthesis, and Antibacterial Activity of Mesoporous Silica Nanoparticles Decorated with Well-Dispersed Silver Nanoparticles

Tian, Yue, Qi, Juanjuan, Zhang, Wei, Cai, Qiang, Jiang, Xingyu·2014·ACS Applied Materials & Interfaces

Abstract

In this study, we exploit a facile, one-pot method to prepare MCM-41 type mesoporous silica nanoparticles decorated with silver nanoparticles (Ag-MSNs). Silver nanoparticles with diameter of 2-10 nm are highly dispersed in the framework of mesoporous silica nanoparticles. These Ag-MSNs possess an enhanced antibacterial effect against both Gram-positive and Gram-negative bacteria by preventing the aggregation of silver nanoparticles and continuously releasing silver ions for one month. The cytotoxicity assay indicates that the effective antibacterial concentration of Ag-MSNs shows little effect on human cells. This report describes an efficient and economical route to synthesize mesoporous silica nanoparticles with uniform silver nanoparticles, and these nanoparticles show promising applications as antibiotics.

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Metadata

Authors
Tian, Y., Qi, J., Zhang, W., Cai, Q., & Jiang, X.
Venue
ACS Applied Materials & Interfaces
Published
2014-07-29
Volume
6
Issue
15
Pages
12038-12045
ISSN
  • 1944-8244 (ISSN-L)
  • 1944-8252
OpenAlex
W2315950804
Cited by
201
References
0
FWCI
8.79
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Facile, One-Pot Synthesis, and Antibacterial Activity of Mesoporous Silica Nanoparticles Decorated with Well-Dispersed Silver Nanoparticles. https://app.cochat.ai/papers/10.1021/am5026424
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Tian, Y., Qi, J., Zhang, W., Cai, Q., & Jiang, X. (2014). Facile, One-Pot Synthesis, and Antibacterial Activity of Mesoporous Silica Nanoparticles Decorated with Well-Dispersed Silver Nanoparticles. ACS Applied Materials & Interfaces. https://doi.org/10.1021/am5026424

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