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Developments in Asymmetric Hydrogenation from an Industrial Perspective
Abstract
Examples of developments in asymmetric hydrogenation from various perspectives, in an effort to improve efficiency, are reported. Discussed in this Account are (1) the improved synthesis of BINAP ligands, (2) the design of SEGPHOS ligands for higher enantioselectivity, (3) a new protocol with fewer reaction steps to synthesize beta-aminoesters, and (4) a novel asymmetric hydrogenation mediated by a copper catalyst.
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Cited by
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Appel, A. M., Bercaw, J. E., Bocarsly, A. B., Dobbek, H., DuBois, D. L., Dupuis, M., Ferry, J. G., Fujita, E., Hille, R., Kenis, P. J. A., et al. (2013) · Chemical Reviews · doi:10.1021/cr300463y · Cited by 2,193
Dub, P. A., & Ikariya, T. (2012) · ACS Catalysis · doi:10.1021/cs300341g · Cited by 386
Enantioselective Chemo‐ and Biocatalysis: Partners in Retrosynthesis
Hönig, M., Sondermann, P., Turner, N. J., & Carreira, E. M. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201612462 · Cited by 284
Metadata
- Authors
- Shimizu, H., Nagasaki, I., Matsumura, K., Sayo, N., & Saito, T.
- Venue
- Accounts of Chemical Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-08-09
- Volume
- 40
- Issue
- 12
- Pages
- 1385-1393
- ISSN
- 0001-4842 (ISSN-L)
- 1520-4898
- OpenAlex
- W1964484777
- Cited by
- 310
- References
- 0
- FWCI
- 7.82
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Developments in Asymmetric Hydrogenation from an Industrial Perspective. https://app.cochat.ai/papers/10.1021/ar700101x
- The paper
- Shimizu, H., Nagasaki, I., Matsumura, K., Sayo, N., & Saito, T. (2007). Developments in Asymmetric Hydrogenation from an Industrial Perspective. Accounts of Chemical Research. https://doi.org/10.1021/ar700101x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.