Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO 2 Fixation
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The article discusses opportunities and challenges in biochemical and chemical catalysis of carbon dioxide fixation. All biological systems must extract energy from their environments to carry out the metabolic processes associated with life itself. Living organisms have evolved to exist in an amazing variety of environments, and they can use and interconvert energy from a variety of sources. The enzymes required to carry out these important metabolic pathways have evolved over billions of years, and they use readily abundant materials from the environment to achieve these important energy conversion processes. All of these metabolic pathways involve the storage and utilization of energy in the form of chemical bonds, and our ability to carry out these same transformations in a controlled and productive manner, independent of natural biological systems, will be critical to the future energy security.
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Development in enzymatic and organometallic CO2 conversion fields is still in its infancy, and considerable effort is needed to understand structural features controlling catalytic activity and achieve practical catalysts.
“However, development in these fields is still in its infancy; considerable effort needs to be dedicated to understanding structural features controlling the catalytic activity and achieving practical catalysts suitable for the conversion of CO2 to useful chemicals.334”
From Technologies and perspectives for achieving carbon neutrality (2021) · cites this paper as [334]
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- Authors
- Appel, A. M., Bercaw, J. E., Bocarsly, A. B., Dobbek, H., DuBois, D. L., Dupuis, M., Ferry, J. G., Fujita, E., Hille, R., Kenis, P. J. A., Kerfeld, C. A., Morris, R. H., Peden, C. H. F., Portis, A. R., Ragsdale, S. W., Rauchfuss, T. B., Reek, J. N. H., Seefeldt, L. C., Thauer, R. K., & Waldrop, G. L.
- Affiliations
- Pacific Northwest National Laboratory (US)
- California Institute of Technology (US)
- Princeton University (US)
- Humboldt-Universität zu Berlin (DE)
- Pennsylvania State University (US)
- Brookhaven National Laboratory (US)
- University of California, Riverside (US)
- University of Illinois Urbana-Champaign (US)
- Joint Genome Institute (US)
- University of Toronto (CA)
- University of Michigan (US)
- University of Amsterdam (NL)
- Utah State University (US)
- Max Planck Institute for Terrestrial Microbiology (DE)
- Louisiana State University (US)
- Corresponding author
- DuBois, Daniel L.
- Ragsdale, Stephen W.
- Rauchfuss, Thomas B.
- ORCID
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-06-14
- Volume
- 113
- Issue
- 8
- Pages
- 6621-6658
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- PMC
- PMC3895110
- OpenAlex
- W2246944211
- Semantic Scholar
- 367edf2e55218a9bdfa641fdc82a76eb39ffa3a5
- Cited by
- 2,193
- References
- 389
- Citations by year
- 2026: 112 · 2025: 156 · 2024: 162 · 2023: 204 · 2022: 213 · 2021: 191 · 2020: 184 · 2019: 192 · 2018: 204 · 2017: 173 · 2016: 158 · 2015: 125 · 2014: 103 · 2013: 16
- FWCI
- 6.20
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Chemical Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- Civil War Book Review (submittedVersion)
- UvA-DARE (University of Amsterdam) (submittedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- U.S. Department of Energy
- Washington State University
- Université de Strasbourg
- University of Illinois at Urbana-Champaign
- Office of Science
- National Institute of General Medical Sciences (R37GM039451)
- Basic Energy Sciences
- Topics
- Physical Sciences › Chemical Engineering › Process Chemistry and Technology › Carbon dioxide utilization in catalysis
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › CO2 Reduction Techniques and Catalysts
- Physical Sciences › Engineering › Mechanical Engineering › Carbon Dioxide Capture Technologies
- Keywords
- CO2 fixation, catalysis, metabolic pathways, energy conversion, enzyme evolution, energy storage, energy security, bioenergy
- MeSH terms
- Aldehyde Oxidoreductases, Cyanobacteria, Biochemistry, Carbon, Carbon Dioxide, Carbon Monoxide, Catalysis, Formate Dehydrogenases, Metals, Multienzyme Complexes, Oxidation-Reduction, Ribulose-Bisphosphate Carboxylase, Carbon-Nitrogen Ligases, Biofuels
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