The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Synthesis and spectral properties of a hydrophobic fluorescent probe: 6-propionyl-2-(dimethylamino)naphthalene
Abstract
Environmentally sensitive fluorescent probes involve two groups, an electron donor and an electron acceptor, attached to an aromatic ring system, and maximal effects may be expected when these groups are as far apart as feasible. The syntheisis, characterization, and spectroscopic properties of 6-propionyl-2-(dimethylamino)naphthalene (PRODAN), a compound that fulfills these conditions, are described. The maximum of emission is at 401 nm in cyclohexane solution and at 531 nm in water solution, indicating an increase of dipole moment of approximately 20 D units on excitation to the lowest singlet state. The effect of temperature upon the spectral distribution and the bandwidth of fluorescence of PRODAN in 1:1 complexes with albumin shows the existence of a dynamic relaxation process of the protein surroundings within th 2-4 ns of the fluorescence lifetime.
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Citations
Cites
McCammon, J. A., Gelin, B. R., & Karplus, M. (1977) · Nature · doi:10.1038/267585a0 · Cited by 2,067
Lakowicz, J. R., & Weber, G. (1973) · Biochemistry · doi:10.1021/bi00745a021 · Cited by 801
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Cited by
Grabowski, Z. R., Rotkiewicz, K., & Rettig, W. (2003) · Chemical Reviews · doi:10.1021/cr940745l · Cited by 3,714
Spectrofluorometric studies of the lipid probe, nile red.
Greenspan, P., & Fowler, S. D. (1985) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34307-8 · Cited by 980
Nile red as a polarity-sensitive fluorescent probe of hydrophobic protein surfaces
Sackett, D. L., & Wolff, J. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90157-6 · Cited by 591
A structural remedy toward bright dipolar fluorophores in aqueous media
Singha, S., Kim, D., Roy, B., Sambasivan, S., Moon, H., Rao, A. S., Kim, J. Y., Joo, T., Park, J. W., Rhee, Y. M., et al. (2015) · Chemical Science · doi:10.1039/c5sc01076d · Cited by 170
Rye, K.-A., Hime, N. J., & Barter, P. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.1.189 · Cited by 65
Metadata
- Authors
- Weber, G., & Farris, F. J.
- Venue
- Biochemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1979-07-10
- Volume
- 18
- Issue
- 14
- Pages
- 3075-3078
- ISSN
- 0006-2960 (ISSN-L)
- 1520-4995
- OpenAlex
- W1994673901
- Cited by
- 854
- References
- 2
- FWCI
- 5.21
- Type
- journal article
- Language
- en
- Open access
- closed
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