The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Encapsulation of Drug Reservoirs in Fibers by Emulsion Electrospinning: Morphology Characterization and Preliminary Release Assessment
Abstract
In this paper, we prepared composite fibers via electrospinning from either W/O or O/W emulsion. SEM images demonstrate the beads-in-string structures in these fibers and proved this technique to be an effective method for microencapsulation. As a practical application, Ca-alginate microspheres, which serve as reservoirs for hydrophilic drugs, were prepared in a reverse emulsion and then incorporated into poly (l-lactic acid) (PLLA) fibers by electrospinning. With the bovine serum albumin (BSA) loaded into the microspheres, the beads-in-string structure thus entrapped hydrophilic proteins in hydrophobic polymeric matrix. In the in vitro release test, BSA, which was released from composite fibers, achieved prolonged release profiles and lower burst release rates than those from naked Ca-alginate microspheres. In comparison with other well-established techniques to prepare microcapsules, such as solvent evaporation and spray-drying techniques, emulsion electrospinning features partly competing, partly complementary characteristics. Extension to other emulsion systems will be able to fabricate new types of functional structures.
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Cites
A Thermally Re-mendable Cross-Linked Polymeric Material
Chen, X., Dam, M. A., Ono, K., Mal, A., Shen, H., Nutt, S. R., Sheran, K., & Wudl, F. (2002) · Science · doi:10.1126/science.1065879 · Cited by 2,645
Biodegradation and biocompatibility of PLA and PLGA microspheres
Anderson, J. M., & Shive, M. S. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00048-3 · Cited by 2,617
Beaded nanofibers formed during electrospinning
Fong, H., Chun, I., & Reneker, D. H. (1999) · Polymer · doi:10.1016/s0032-3861(99)00068-3 · Cited by 2,553
Polymeric system for dual growth factor delivery
Richardson, T. P., Peters, M. C., Ennett, A. B., & Mooney, D. J. (2001) · Nature Biotechnology · doi:10.1038/nbt1101-1029 · Cited by 1,752
Protein release from alginate matrices
Gombotz, W. R., & Wee, S. F. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.007 · Cited by 1,609
Protein release from alginate matrices
Gombotz, W. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00124-5 · Cited by 1,550
Kenawy, E.-R., Bowlin, G. L., Mansfield, K., Layman, J., Simpson, D. G., Sanders, E. H., & Wnek, G. E. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00041-x · Cited by 1,311
Micro/Nano encapsulation via electrified coaxial liquid jets
Loscertales, I. G., Barrero, A., Guerrero, I., Cortijo, R., Marquez, M., & Gañán-Calvo, A. M. (2002) · Science · doi:10.1126/science.1067595 · Cited by 1,017
Bending instability in electrospinning of nanofibers
Yarin, A. L., Koombhongse, S., & Reneker, D. H. (2001) · Journal of Applied Physics · doi:10.1063/1.1333035 · Cited by 1,006
Freitas, S., Merkle, H. P., & Gander, B. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.10.015 · Cited by 923
Cited by
One‐Dimensional Composite Nanomaterials: Synthesis by Electrospinning and Their Applications
Lu, X., Wang, C., & Wei, Y. (2009) · Small · doi:10.1002/smll.200900445 · Cited by 874
Electrospinning for drug delivery applications: A review
Luraghi, A., Peri, F., & Moroni, L. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.03.033 · Cited by 746
Yang, G., Li, X., He, Y., Ma, J., Ni, G., & Zhou, S. (2018) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2017.12.003 · Cited by 336
Applications of electrospun nanofibers
Fang, J., Niu, H., Lin, T., & Wang, X. (2008) · Science Bulletin · doi:10.1007/s11434-008-0319-0 · Cited by 313
Oliveira, J. E., Medeiros, E. S., Cardozo, L., Voll, F., Madureira, E. H., Mattoso, L. H. C., & Assis, O. B. G. (2013) · Materials Science and Engineering: C · doi:10.1016/j.msec.2012.10.032 · Cited by 70
Metadata
- Authors
- Qi, H., Hu, P., Xu, J., & Wang, A.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-07-20
- Volume
- 7
- Issue
- 8
- Pages
- 2327-2330
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W2079144689
- Cited by
- 323
- References
- 18
- FWCI
- 6.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- Qi, H., Hu, P., Xu, J., & Wang, A. (2006). Encapsulation of Drug Reservoirs in Fibers by Emulsion Electrospinning: Morphology Characterization and Preliminary Release Assessment. Biomacromolecules. https://doi.org/10.1021/bm060264z
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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