The DOI matches its Crossref record.
Enzyme-Responsive Release of Encapsulated Proteins from Biodegradable Hollow Capsules
Abstract
Biodegradable hollow capsules encapsulating proteins were prepared via layer-by-layer assembly of chitosan and dextran sulfate on protein-entrapping mesoporous silica particles and the subsequent removal of the silica. The enzymatic degradation of the capsules in the presence of chitosanase was explored by scanning electron microscopy (SEM). With increasing time, the chitosan component was degraded by chitosanase, and the capsules began to deform and were finally destroyed. Sustained release of the encapsulated proteins was attained by using the enzymatic degradation of the hollow capsules. The release behavior was successfully manipulated by altering the charge of capsule surface.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Motornov, M., Roiter, Y., Tokarev, I., & Minko, S. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2009.10.004 · Cited by 773
Template Synthesis of Nanostructured Materials via Layer-by-Layer Assembly
Wang, Y., Angelatos, A. S., & Caruso, F. (2008) · Chemistry of Materials · doi:10.1021/cm7024813 · Cited by 767
Enzyme-responsive polymeric assemblies, nanoparticles and hydrogels
Hu, J., Zhang, G., & Liu, S. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35103j · Cited by 722
Stimuli-responsive LbL capsules and nanoshells for drug delivery
Delcea, M., Möhwald, H., & Skirtach, A. G. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.03.010 · Cited by 685
Stimuli-Responsive Polymers and Their Applications in Nanomedicine
Cabane, E., Zhang, X., Langowska, K., Palivan, C. G., & Meier, W. (2012) · Biointerphases · doi:10.1007/s13758-011-0009-3 · Cited by 468
Metadata
- Authors
- Itoh, Y., Matsusaki, M., Kida, T., & Akashi, M.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-08-29
- Volume
- 7
- Issue
- 10
- Pages
- 2715-2718
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W2050297071
- Cited by
- 204
- References
- 0
- FWCI
- 9.49
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Enzyme-Responsive Release of Encapsulated Proteins from Biodegradable Hollow Capsules. https://app.cochat.ai/papers/10.1021/bm060289y
- The paper
- Itoh, Y., Matsusaki, M., Kida, T., & Akashi, M. (2006). Enzyme-Responsive Release of Encapsulated Proteins from Biodegradable Hollow Capsules. Biomacromolecules. https://doi.org/10.1021/bm060289y
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
