The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Redox-Responsive, Core-Cross-Linked Micelles Capable of On-Demand, Concurrent Drug Release and Structure Disassembly
Open accessAbstract
We developed camptothecin (CPT)-conjugated, core-cross-linked (CCL) micelles that are subject to redox-responsive cleavage of the built-in disulfide bonds, resulting in disruption of the micellar structure and rapid release of CPT. CCL micelles were prepared via coprecipitation of disulfide-containing CPT-poly(tyrosine(alkynyl)-OCA) conjugate and monomethoxy poly(ethylene glycol)-b-poly(tyrosine(alkynyl)-OCA), followed by cross-linking of the micellar core via azide-alkyne click chemistry. CCL micelles exhibited excellent stability under physiological conditions, while they underwent rapid dissociation in reduction circumstance, resulting in burst release of CPT. These redox-responsive CCL micelles showed enhanced cytotoxicity against human breast cancer cells in vitro.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Core-cross-linked polymeric micelles as paclitaxel carriers
Shuai, X., Merdan, T., Schaper, A. K., Xi, F., & Kissel, T. (2004) · Bioconjugate Chemistry · doi:10.1021/bc034113u · Cited by 333
Yang, Z., Zheng, S., Harrison, W. J., Harder, J., Wen, X., Gelovani, J. G., Qiao, A., & Li, C. (2007) · Biomacromolecules · doi:10.1021/bm7005399 · Cited by 130
Design of reversibly core cross-linked micelles sensitive to reductive environment
Cajot, S., Lautram, N., Passirani, C., & Jérôme, C. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.03.026 · Cited by 76
Cited by
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
Karimi, M., Ghasemi, A., Sahandi Zangabad, P., Rahighi, R., Moosavi Basri, S. M., Mirshekari, H., Amiri, M., Shafaei Pishabad, Z., Aslani, A., Bozorgomid, M., et al. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00798d · Cited by 1,519
Ramasamy, T., Ruttala, H. B., Gupta, B., Poudel, B. K., Choi, H.-G., Yong, C. S., & Kim, J. O. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.04.043 · Cited by 373
Recent advances in stimuli-responsive polymeric micelles via click chemistry
Dai, Y., Chen, X., & Zhang, X. (2019) · Polymer Chemistry · doi:10.1039/c8py01174e · Cited by 87
pH-Responsive Lignin-Based Nanomicelles for Oral Drug Delivery
Cheng, L., Deng, B., Luo, W., Nie, S., Liu, X., Yin, Y., Liu, S., Wu, Z., Zhan, P., Zhang, L., et al. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b08171 · Cited by 77
Strategies for the synthesis of block copolymers with biodegradable polyester segments
Diaz, C., & Mehrkhodavandi, P. (2021) · Polymer Chemistry · doi:10.1039/d0py01534b · Cited by 74
Metadata
- Authors
- Wang, H., Tang, L., Tu, C., Song, Z., Yin, Q., Yin, L., Zhang, Z., & Cheng, J.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-09-23
- Volume
- 14
- Issue
- 10
- Pages
- 3706-3712
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W1966421987
- Cited by
- 172
- References
- 3
- FWCI
- 8.87
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
