The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Homogeneous Quaternization of Cellulose in NaOH/Urea Aqueous Solutions as Gene Carriers
Abstract
Quaternized celluloses (QCs) were homogeneously synthesized by reacting cellulose with 3-chloro-2-hydroxypropyltrimethylammonium chloride (CHPTAC) in NaOH/urea aqueous solutions. The structure and solution properties of the QCs were characterized by using elemental analysis, FTIR, (13)C NMR, SEC-LLS, viscometer, and zeta-potential measurement. The results revealed that water-soluble QCs, with a degree of substitution (DS) value of 0.20-0.63, could be obtained by adjusting the molar ratio of CHPTAC to anhydroglucose unit (AGU) of cellulose and the reaction time. The QC solutions in water displayed a typical polyelectrolyte behavior, and the intrinsic viscosity ([eta]) value determined from the Fuoss-Strauss method increased with increasing DS value. Moreover, two QC samples (DS = 0.46 and 0.63) were selected and studied as gene carriers. The results of gel retardation assay suggested that QCs could condense DNA efficiently. QCs displayed relatively lower cytotoxicity as compared with PEI, and QC/DNA complexes exhibited effective transfection compared to the naked DNA in 293T cells. The quaternized cellulose derivatives prepared in NaOH/urea aqueous solutions could be considered as promising nonviral gene carriers.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
Merdan, T., Kopec̆ek, J., & Kissel, T. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00046-7 · Cited by 785
Polyelectrolytes. II. Poly‐4‐vinylpyridonium chloride and poly‐4‐vinyl‐N‐n‐butylpyridonium bromide
Fuoss, R. M., & Strauss, U. P. (1948) · Journal of Polymer Science · doi:10.1002/pol.1948.120030211 · Cited by 448
Cationic starch: an effective flocculating agent
Pal, S., Mal, D., & Singh, R. P. (2005) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2004.06.047 · Cited by 395
Infrared study of arabinoxylans
Kačuráková, M., Ebringerová, A., Hirsch, J., & Hromàdková, Z. (1994) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.2740660323 · Cited by 230
A viscosity-molecular weight relationship for cellulose in cadoxen and a hydrodynamic interpretation
Brown, W., & Wikström, R. (1965) · European Polymer Journal · doi:10.1016/0014-3057(65)90041-8 · Cited by 197
Cationic functionalisation of cellulose using a choline based ionic liquid analogue
Abbott, A. P., Bell, T. J., Handa, S., & Stoddart, B. (2006) · Green Chemistry · doi:10.1039/b605258d · Cited by 184
Preparation and characterization of a quaternary ammonium derivative of konjac glucomannan
Yu, H., Huang, Y., Ying, H., & Xiao, C. (2006) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2006.08.024 · Cited by 156
Rheology of polysaccharide systems
Lapasin, R., & Pricl, S. (1995) · Springer eBooks · doi:10.1007/978-1-4615-2185-3_4 · Cited by 122
Study on the cationic modification and dyeing of ramie fiber
Liu, Z., Liu, Z.-T., Yang, Y., Zhang, L., Liu, Z.-W., Liu, Z.-W., & Xiong, H. (2007) · Cellulose · doi:10.1007/s10570-007-9117-0 · Cited by 93
Self-citationInteractions of ibuprofen with cationic polysaccharides in aqueous dispersions and hydrogels
Rodrı́guez, R., Alvarez‐Lorenzo, C., & Concheiro, Á. (2003) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2003.09.004 · Cited by 92
Size-dependent properties of M-PEIs nanogels for gene delivery in cancer cells
Xu, D., Yao, S.-D., Liu, Y.-B., Sheng, K., Hong, J., Gong, P., & Dong, L. (2007) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2007.01.050 · Cited by 76
Zhou, H., Song, G., Zhang, Y., et al. (2001) · Macromolecular Chemistry and Physics · doi:10.1002/1521-3935(20011001)202:15<3057::aid-macp3057>3.0.co;2-5 · Cited by 30
Cited by
Ionic Liquids and Their Interaction with Cellulose
Pinkert, A., Marsh, K. N., Pang, S., & Staiger, M. P. (2009) · Chemical Reviews · doi:10.1021/cr9001947 · Cited by 1,508
Recent advances in surface-modified cellulose nanofibrils
Rol, F., Belgacem, M. N., Gandini, A., & Bras, J. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2018.09.002 · Cited by 698
Xie, H., Du, H., Yang, X., & Si, C. (2018) · International Journal of Polymer Science · doi:10.1155/2018/7923068 · Cited by 328
Swelling Behaviors of pH- and Salt-Responsive Cellulose-Based Hydrogels
Chang, C., He, M., Zhou, J., & Zhang, L. (2011) · Macromolecules · doi:10.1021/ma102801f · Cited by 300
Self-citationCellulose Solvents – Remarkable History, Bright Future
Liebert, T. (2010) · ACS Symposium Series · doi:10.1021/bk-2010-1033.ch001 · Cited by 250
Metadata
- Authors
- Song, Y., Sun, Y., Zhang, X., Zhou, J., & Zhang, L.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-07-19
- Volume
- 9
- Issue
- 8
- Pages
- 2259-2264
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W2066058992
- Cited by
- 289
- References
- 12
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
