The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Self-Assembled Fmoc-Peptides as a Platform for the Formation of Nanostructures and Hydrogels
Abstract
Hydrogels are of great interest as a class of materials for tissue engineering, axonal regeneration, and controlled drug delivery, as they offer 3D interwoven scaffolds to support the growth of cells. Herein, we extend the family of the aromatic Fmoc-dipeptides with a library of new Fmoc-peptides, which include natural and synthetic amino acids with an aromatic nature. We describe the self-assembly of these Fmoc-peptides into various structures and characterize their distinctive molecular and physical properties. Moreover, we describe the fabrication of the bioactive RGD sequence into a hydrogel. This unique material offers new opportunities for developing cell-adhesive biomedical hydrogel scaffolds, as well as for establishing strategies to modify surfaces with bioactive materials.
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Cites
Hydrogels for tissue engineering: scaffold design variables and applications
Drury, J. L., & Mooney, D. J. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00340-5 · Cited by 5,136
Design and self-assembly of two-dimensional DNA crystals
Winfree, E., Liu, F., Wenzler, L. A., & Seeman, N. C. (1998) · Nature · doi:10.1038/28998 · Cited by 2,857
A tough biodegradable elastomer
Wang, Y., Ameer, G. A., Sheppard, B. J., & Langer, R. (2002) · Nature Biotechnology · doi:10.1038/nbt0602-602 · Cited by 1,314
Cited by
Functional π-Gelators and Their Applications
Babu, S. S., Praveen, V. K., & Ajayaghosh, A. (2014) · Chemical Reviews · doi:10.1021/cr400195e · Cited by 1,725
Three-dimensional in vitro cell culture models in drug discovery and drug repositioning
Langhans, S. A. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00006 · Cited by 1,522
Self-assembling peptide scaffolds for regenerative medicine
Matson, J. B., & Stupp, S. I. (2012) · Chem. Commun. · doi:10.1039/c1cc15551b · Cited by 501
Tao, K., Levin, A., Adler-Abramovich, L., & Gazit, E. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00889a · Cited by 482
Self-citationAmino Acids and Peptide‐Based Supramolecular Hydrogels for Three‐Dimensional Cell Culture
Dou, X., & Feng, C. (2017) · Advanced Materials · doi:10.1002/adma.201604062 · Cited by 355
Metadata
- Authors
- Orbach, R., Adler-Abramovich, L., Zigerson, S., Mironi-Harpaz, I., Seliktar, D., & Gazit, E.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-08-25
- Volume
- 10
- Issue
- 9
- Pages
- 2646-2651
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W2069451261
- Cited by
- 330
- References
- 3
- FWCI
- 9.98
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
