The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
Amino Acids and Peptide‐Based Supramolecular Hydrogels for Three‐Dimensional Cell Culture
Abstract
Supramolecular hydrogels assembled from amino acids and peptide‐derived hydrogelators have shown great potential as biomimetic three‐dimensional (3D) extracellular matrices because of their merits over conventional polymeric hydrogels, such as non‐covalent or physical interactions, controllable self‐assembly, and biocompatibility. These merits enable hydrogels to be made not only by using external stimuli, but also under physiological conditions by rationally designing gelator structures, as well as in situ encapsulation of cells into hydrogels for 3D culture. This review will assess current progress in the preparation of amino acids and peptide‐based hydrogels under various kinds of external stimuli, and in situ encapsulation of cells into the hydrogels, with a focus on understanding the associations between their structures, properties, and functions during cell culture, and the remaining challenges in this field. The amino acids and peptide‐based hydrogelators with rationally designed structures have promising applications in the fields of regenerative medicine, tissue engineering, and pre‐clinical evaluation.
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Cites
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Recent advances in biomaterials for 3D scaffolds: A review
Nikolova, M. P., & Chavali, M. S. (2019) · Bioactive Materials · doi:10.1016/j.bioactmat.2019.10.005 · Cited by 907
Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Self‐Assembled Peptide‐Based Nanomaterials for Biomedical Imaging and Therapy
Qi, G., Gao, Y., Wang, L., & Wang, H. (2018) · Advanced Materials · doi:10.1002/adma.201703444 · Cited by 527
Hu, H., Dong, L., Bu, Z., Shen, Y., Luo, J., Zhang, H., Zhao, S., Lv, F., & Liu, Z. (2020) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2020.1778883 · Cited by 310
Pan, X., Wang, Q., He, P., Liu, K., Ni, Y., Ouyang, X., Chen, L., Huang, L., Wang, H., & Tan, Y. (2019) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.9b00579 · Cited by 109
Metadata
- Authors
- Dou, X., & Feng, C.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2017-01-23
- Volume
- 29
- Issue
- 16
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2580365938
- Cited by
- 355
- References
- 135
- FWCI
- 12.02
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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