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Protein Separations Using Colloidal Magnetic Nanoparticles

Bucak, Seyda, Jones, Deverraux A., Laibinis, Paul E., Hatton, T. Alan·2003·Biotechnology Progress

Abstract

Phospholipid‐coated colloidal magnetic nanoparticles with mean magnetite core size of 8 nm are shown to be effective ion exchange media for the recovery and separation of proteins from protein mixtures. These particles have high adsorptive capacities (up to 1200 mg protein/mL adsorbent, an order of magnitude larger than the best commercially available adsorbents) and exhibit none of the diffusional resistances offered by conventional porous ion exchange media. Protein‐laden particles are readily recovered from the feed solution using high‐gradient magnetic filtration.

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Metadata

Authors
Bucak, S., Jones, D. A., Laibinis, P. E., & Hatton, T. A.
Venue
Biotechnology Progress
Publisher
Wiley
Published
2003-01
Volume
19
Issue
2
Pages
477-484
ISSN
  • 1520-6033 (ISSN-L)
  • 8756-7938
OpenAlex
W2151470854
Cited by
324
References
0
FWCI
6.97
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Protein Separations Using Colloidal Magnetic Nanoparticles. https://app.cochat.ai/papers/10.1021/bp0200853
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Bucak, S., Jones, D. A., Laibinis, P. E., & Hatton, T. A. (2003). Protein Separations Using Colloidal Magnetic Nanoparticles. Biotechnology Progress. https://doi.org/10.1021/bp0200853

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.