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Cited by 251

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Bactericidal Properties of Flat Surfaces and Nanoparticles Derivatized with Alkylated Polyethylenimines

Lin, Jian, Qiu, Shuyi, Lewis, Kim, Klibanov, Alexander M.·2002·Biotechnology Progress

Abstract

We previously discovered that covalently coating glass and plastic slides with certain long poly(vinyl‐ N ‐alkylpyridinium) chains enables the resultant surfaces to kill a variety of airborne and waterborne bacteria on contact. In the present study, these findings have been extended to an unrelated polymer class, polyethylenimines (PEIs). Alkylated PEIs attached to flat macroscopic surfaces and to those of nanoparticles make these materials highly bactericidal toward both Gram‐positive and Gram‐negative pathogenic bacteria. Systematic chemical modifications of the immobilized PEI conducted herein shed light on the relationship between the structure of the polymer and the antibacterial efficiency of the resultant coating.

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Metadata

Authors
Lin, J., Qiu, S., Lewis, K., & Klibanov, A. M.
Venue
Biotechnology Progress
Publisher
Wiley
Published
2002-01
Volume
18
Issue
5
Pages
1082-1086
ISSN
  • 1520-6033 (ISSN-L)
  • 8756-7938
OpenAlex
W2162963173
Cited by
251
References
0
FWCI
3.67
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Bactericidal Properties of Flat Surfaces and Nanoparticles Derivatized with Alkylated Polyethylenimines. https://app.cochat.ai/papers/10.1021/bp025597w
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Lin, J., Qiu, S., Lewis, K., & Klibanov, A. M. (2002). Bactericidal Properties of Flat Surfaces and Nanoparticles Derivatized with Alkylated Polyethylenimines. Biotechnology Progress. https://doi.org/10.1021/bp025597w

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.