Cited by 485Antimicrobial agents and applicationsDyeing and Modifying Textile FibersPolymer Surface Interaction Studies

Antimicrobial Polymers

Jain, Anjali, Duvvuri, L. Sailaja, Farah, Shady, Beyth, Nurit, Domb, Abraham J., Khan, Wahid·2014·Advanced Healthcare Materials

Abstract

Better health is basic requirement of human being, but the rapid growth of harmful pathogens and their serious health effects pose a significant challenge to modern science. Infections by pathogenic microorganisms are of great concern in many fields such as medical devices, drugs, hospital surfaces/furniture, dental restoration, surgery equipment, health care products, and hygienic applications (e.g., water purification systems, textiles, food packaging and storage, major or domestic appliances etc.) Antimicrobial polymers are the materials having the capability to kill/inhibit the growth of microbes on their surface or surrounding environment. Recently, they gained considerable interest for both academic research and industry and were found to be better than their small molecular counterparts in terms of enhanced efficacy, reduced toxicity, minimized environmental problems, resistance, and prolonged lifetime. Hence, efforts have focused on the development of antimicrobial polymers with all desired characters for optimum activity. In this Review, an overview of different antimicrobial polymers, their mechanism of action, factors affecting antimicrobial activity, and application in various fields are given. Recent advances and the current clinical status of these polymers are also discussed.

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Registry

Crossref · 10.1002/adhm.201400418

Cites

135 of 135 references verified0 citation errors · 0 not checkable

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  • QPEI is a synthetic, non-biodegradable, cationic polymer with primary, secondary, and tertiary amine functionalities that can undergo chemical modifications to produce desirable physicochemical properties.

    “The QPEI is a synthetic, non-biodegradable, cationic polymer with primary, secondary and tertiary amine functionalities, which may be subjected to a wide range of chemical modifications to produce desirable physicochemical properties [16].”

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Authors
Jain, A., Duvvuri, L. S., Farah, S., Beyth, N., Domb, A. J., & Khan, W.
Affiliations
  • National Institute of Pharmaceutical Education and Research (IN)
  • Hebrew University of Jerusalem (IL)
Corresponding author
  • Domb, Abraham J.
  • Khan, Wahid
Venue
Advanced Healthcare Materials
Publisher
Wiley
Published
2014-11-19
Volume
3
Issue
12
Pages
1969-1985
ISSN
  • 2192-2640 (ISSN-L)
  • 2192-2659
OpenAlex
W4211217504
Cited by
485
References
135
Citations by year
2026: 17 · 2025: 31 · 2024: 57 · 2023: 58 · 2022: 49 · 2021: 70 · 2020: 46 · 2019: 49 · 2018: 36 · 2017: 24 · 2016: 32 · 2015: 5 · 2014: 4
FWCI
1.17
Type
journal article
Language
en
Open access
closed
Locations
  • Advanced Healthcare Materials (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
  • Physical Sciences › Engineering › Building and Construction › Dyeing and Modifying Textile Fibers
  • Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
Keywords
antimicrobial polymers, antimicrobial mechanisms, antimicrobial activity, pathogenic microorganisms, medical devices, hospital surfaces, food packaging, textiles, water purification, dental restorations, surgical equipment, clinical application
MeSH terms
Animals, Anti-Infective Agents, Clinical Trials as Topic, Humans, Polymers, Swine, Drug Delivery Systems, Coated Materials, Biocompatible, Nanostructures

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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