The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Peptide- and Protein-Based Hydrogels
Abstract
Hydrogels are polymeric networks, capable of absorbing large amounts of water and biological fluids. They are insoluble due to the presence of chemical or physical cross-links between the constituents. Hydrogels are promising materials for use as injectable biomaterials due to their high water content, tunable viscoelasticity, and biocompatibility. Peptides and proteins are important building blocks in the design of hydrogels, since they are easily degraded by the body and display a high biocompatibility. This review aims to give an overview of hydrogels in which peptides and proteins are structural elements of the polymer network. The review starts with hydrogels derived from naturally occurring structural proteins, followed by all-protein and peptide-based synthetic systems. Next, hybrid hydrogels composed of synthetic polymeric and peptide structural elements will be discussed. The potential of these hydrogels is illustrated with applications that are mainly derived from the field of tissue engineering.
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Citations
Cites
Hydrogels for tissue engineering: scaffold design variables and applications
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RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS
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Cited by
Stimulus-responsive hydrogels: theory, modern advances, and applications
Koetting, M. C., Peters, J. T., Steichen, S. D., & Peppas, N. A. (2015) · Materials Science and Engineering: R: Reports · doi:10.1016/j.mser.2015.04.001 · Cited by 1,191
A review on latest innovations in natural gums based hydrogels: Preparations & applications
Ahmad, S., Ahmad, M., Manzoor, K., Purwar, R., & Ikram, S. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.06.113 · Cited by 332
Self-Assembling Peptide EAK16 and RADA16 Nanofiber Scaffold Hydrogel
Gelain, F., Luo, Z., & Zhang, S. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00690 · Cited by 267
Poly(lactic acid) based hydrogels
Basu, A., Kunduru, K. R., Doppalapudi, S., Domb, A. J., & Khan, W. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.07.004 · Cited by 188
Recent advances in the structure, synthesis, and applications of natural polymeric hydrogels
Gul, K., Gan, R.-Y., Sun, C.-X., Jiao, G., Wu, D.-T., Li, H.-B., Kenaan, A., Corke, H., & Fang, Y.-P. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1870034 · Cited by 144
Metadata
- Authors
- Jonker, A. M., Löwik, D. W. P. M., & van Hest, J. C. M.
- Venue
- Chemistry of Materials
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-01-09
- Volume
- 24
- Issue
- 5
- Pages
- 759-773
- ISSN
- 0897-4756 (ISSN-L)
- 1520-5002
- OpenAlex
- W1991918935
- Cited by
- 504
- References
- 6
- FWCI
- 8.68
- Type
- journal article
- Language
- en
- Open access
- closed
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