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Peptide Coupling Reagents, More than a Letter Soup
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTPeptide Coupling Reagents, More than a Letter SoupAyman El-Faham*†‡ and Fernando Albericio*†§∥View Author Information† Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain‡ Alexandria University, Faculty of Science, Department of Chemistry, P.O. Box 426, Ibrahimia, 21321 Alexandria, Egypt§ CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain.∥ Department of Organic Chemistry, University of Barcelona, Martí i Franqués 1-11, 08028-Barcelona, SpainE-mail addresses: [email protected]; [email protected]Cite this: Chem. Rev. 2011, 111, 11, 6557–6602Publication Date (Web):August 26, 2011Publication History Received14 February 2010Published online26 August 2011Published inissue 9 November 2011https://pubs.acs.org/doi/10.1021/cr100048whttps://doi.org/10.1021/cr100048wreview-articleACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views57025Altmetric-Citations906LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anions,Peptides and proteins,Reaction products,Reagents,Salts Get e-Alerts
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“In current chemical peptide synthesis methods, peptide chain elongation is almost exclusively executed from the C-terminus to the N-terminus (C → N) by employing Nα-protected amino acids as the building blocks.11,37”
From Ynamide Coupling Reagents: Origin and Advances (2024) · cites this paper as [11]
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Metadata
- Authors
- El-Faham, A., & Albericio, F.
- Affiliations
- Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-08-26
- Volume
- 111
- Issue
- 11
- Pages
- 6557-6602
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2041513075
- Cited by
- 1,245
- References
- 300
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- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Analysis
- Physical Sciences › Chemistry › Organic Chemistry › Click Chemistry and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Structural Characterization
- Keywords
- peptide coupling reagents, peptide synthesis, peptide bond formation, protecting groups, protecting group chemistry, peptide synthesis reagents, peptide functionalization, peptide purification
- MeSH terms
- Indicators and Reagents, Peptides
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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