The DOI matches its Crossref record; 217 of the 217 references it cites were found in a registry or an index.
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
Open accessAbstract
Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families: the α-, β-, γ-, δ-, and ζ-CAs The α- β- and δ-CAs contain a Zn(II) ion at the active site, the γ-CAs are probably Fe(II) enzymes (but they are active also with Zn(II) or Co(II) ions), while the metal ion is usually replaced by cadmium in the ζ-CAs. Herein we report a state of the art structural crystallographyc investigation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Arzneimittelforschung: Eine Zukunftsoption für Ärzte?
Bethke, T. D. (2012) · Der Pneumologe · doi:10.1007/s10405-012-0601-3 · Cited by 3,261
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
Supuran, C. T. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2467 · Cited by 3,192
Self-citationCarbonic anhydrase: chemistry, physiology, and inhibition
Maren, T. H. (1967) · Physiological Reviews · doi:10.1152/physrev.1967.47.4.595 · Cited by 1,889
Antioxidant and radical scavenging properties of curcumin
Ak, T., & Gülçin, İ. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.05.003 · Cited by 1,651
Supuran, C. T., Scozzafava, A., & Casini, A. (2003) · Medicinal Research Reviews · doi:10.1002/med.10025 · Cited by 1,449
Self-citationAntioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid)
Gülçin, İ. (2006) · Toxicology · doi:10.1016/j.tox.2005.09.011 · Cited by 1,157
Esterase Activities of Human Carbonic Anhydrases B and C
Verpoorte, J. A., Mehta, S., & Edsall, J. T. (1967) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)95800-x · Cited by 1,064
Structure and mechanism of carbonic anhydrase
Lindskog, S. (1997) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(96)00198-2 · Cited by 1,022
Biochemical markers of muscular damage
Brancaccio, P., Lippi, G., & Maffulli, N. (2010) · cclm · doi:10.1515/cclm.2010.179 · Cited by 839
Cited by
Hu, Y., Li, C.-Y., Wang, X.-M., Yang, Y.-H., & Zhu, H.-L. (2014) · Chemical Reviews · doi:10.1021/cr400131u · Cited by 607
Le Roy, N., Jackson, D. J., Marie, B., Ramos-Silva, P., & Marin, F. (2014) · Frontiers in Zoology · doi:10.1186/s12983-014-0075-8 · Cited by 131
Nguyen, G. T. H., Bennett, J. L., Liu, S., Hancock, S. E., Winter, D. L., Glover, D. J., & Donald, W. A. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.1c10408 · Cited by 66
Metadata
- Authors
- Alterio, V., Di Fiore, A., D’Ambrosio, K., Supuran, C. T., & De Simone, G.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-05-18
- Volume
- 112
- Issue
- 8
- Pages
- 4421-4468
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W1972547175
- Cited by
- 1,238
- References
- 217
- FWCI
- 6.03
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms? https://app.cochat.ai/papers/10.1021/cr200176r
- The paper
- Alterio, V., Di Fiore, A., D’Ambrosio, K., Supuran, C. T., & De Simone, G. (2012). Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms? Chemical Reviews. https://doi.org/10.1021/cr200176r
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
