The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Comparative Toxicity of Nanoparticulate ZnO, Bulk ZnO, and ZnCl2 to a Freshwater Microalga (Pseudokirchneriella subcapitata): The Importance of Particle Solubility
Abstract
Metal oxide nanoparticles are finding increasing application in various commercial products, leading to concerns for their environmental fate and potential toxicity. It is generally assumed that nanoparticles will persist as small particles in aquatic systems and that their bioavailability could be significantly greater than that of larger particles. The current study using nanoparticulate ZnO (ca. 30 nm) has shown that this is not always so. Particle characterization using transmission electron microscopy and dynamic light scattering techniques showed that particle aggregation is significant in a freshwater system, resulting in flocs ranging from several hundred nanometers to several microns. Chemical investigations using equilibrium dialysis demonstrated rapid dissolution of ZnO nanoparticles in a freshwater medium (pH 7.6), with a saturation solubility in the milligram per liter range, similar to that of bulk ZnO. Toxicity experiments using the freshwater alga Pseudokirchneriella subcapitata revealed comparable toxicity for nanoparticulate ZnO, bulk ZnO, and ZnCl2, with a 72-h IC50 value near 60 microg Zn/ L, attributable solely to dissolved zinc. Care therefore needs to be taken in toxicity testing in ascribing toxicity to nanoparticles per se when the effects may be related, at least in part, to simple solubility.
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Brunner, T. J., Wick, P., Manser, P., Spohn, P., Grass, R. N., Limbach, L. K., Bruinink, A., & Stark, W. J. (2006) · Environmental Science & Technology · doi:10.1021/es052069i · Cited by 1,385
Limbach, L. K., Li, Y., Grass, R. N., Brunner, T. J., Hintermann, M. A., Muller, M., Gunther, D., & Stark, W. J. (2005) · Environmental Science & Technology · doi:10.1021/es051043o · Cited by 779
Cited by
Nanomaterials in the environment: Behavior, fate, bioavailability, and effects
Klaine, S. J., Alvarez, P. J. J., Batley, G. E., Fernandes, T. F., Handy, R. D., Lyon, D. Y., Mahendra, S., McLaughlin, M. J., & Lead, J. R. (2008) · Environmental Toxicology and Chemistry · doi:10.1897/08-090.1 · Cited by 2,764
Self-citationLi, Q., Mahendra, S., Lyon, D. Y., Brunet, L., Liga, M. V., Li, D., & Alvarez, P. J. J. (2008) · Water Research · doi:10.1016/j.watres.2008.08.015 · Cited by 2,385
Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi
Navarro, E., Baun, A., Behra, R., Hartmann, N. B., Filser, J., Miao, A.-J., Quigg, A., Santschi, P. H., & Sigg, L. (2008) · Ecotoxicology · doi:10.1007/s10646-008-0214-0 · Cited by 1,772
Karlsson, H. L., Cronholm, P., Gustafsson, J., & Möller, L. (2008) · Chemical Research in Toxicology · doi:10.1021/tx800064j · Cited by 1,480
Farré, M. L., Pérez, S., Kantiani, L., & Barceló, D. (2008) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2008.09.010 · Cited by 1,009
Metadata
- Authors
- Franklin, N. M., Rogers, N. J., Apte, S. C., Batley, G. E., Gadd, G. E., & Casey, P. S.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-11-17
- Volume
- 41
- Issue
- 24
- Pages
- 8484-8490
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2007792678
- Cited by
- 1,282
- References
- 2
- FWCI
- 23.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Franklin, N. M., Rogers, N. J., Apte, S. C., Batley, G. E., Gadd, G. E., & Casey, P. S. (2007). Comparative Toxicity of Nanoparticulate ZnO, Bulk ZnO, and ZnCl2 to a Freshwater Microalga (Pseudokirchneriella subcapitata): The Importance of Particle Solubility. Environmental Science & Technology. https://doi.org/10.1021/es071445r
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