The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Experimental p Ka Determination for Perfluorooctanoic Acid (PFOA) and the Potential Impact of p Ka Concentration Dependence on Laboratory-Measured Partitioning Phenomena and Environmental Modeling
Abstract
An accurately measured equilibrium acid dissociation constant (pKa) is essential for understanding and predicting the fate of perfluorocarboxylic acids (PFCAs) in the environment. The aqueous pKa of perfluorooctanoic acid (PFOA) has been determined potentiometrically using a standard water-methanol mixed solvent approach and was found to be 3.8 +/- 0.1. The acidity of PFOA is thus considerably weaker than its shorter-chain PFCA homologues. This was attributed to differences in molecular and electronic structure, coupled with solvation effects. The pKa of PFOA was suppressed to approximately 2.3 at higher concentrations because of the aggregation of perfluorooctanoate (PFO). Often, PFCA partion coefficients are determined at concentrations above those found in the environment. Thus, it was suggested that a pKa correction factor, which accounts for this concentration-dependent shift in acid/base equilibrium, should be applied to PFCA partition efficients before they are implemented in environmental fate models. A pKa of 3.8 +/- 0.1 suggests that a considerable concentration of the PFCA exists as the neutral species in the aqueous environment for example, in typical Ontario rainwater, it is approximately 17%. Transport, fate, and partitioning models have often ignored the presence this species completely. The environmental dissemination of PFCAs could, in part, be explained by considering the role of the neutral species.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Sorption of Perfluorinated Surfactants on Sediments
Higgins, C. P., & Luthy, R. G. (2006) · Environmental Science & Technology · doi:10.1021/es061000n · Cited by 1,563
Ellis, D. A., Martin, J. W., De Silva, A. O., Mabury, S. A., Hurley, M. D., Sulbaek Andersen, M. P., & Wallington, T. J. (2004) · Environmental Science & Technology · doi:10.1021/es049860w · Cited by 1,000
Self-citationThe p K a Values of PFOA and Other Highly Fluorinated Carboxylic Acids
Goss, K.-U. (2008) · Environmental Science & Technology · doi:10.1021/es702192c · Cited by 471
Cited by
Buck, R. C., Franklin, J., Berger, U., Conder, J. M., Cousins, I. T., de Voogt, P., Jensen, A. A., Kannan, K., Mabury, S. A., & van Leeuwen, S. P. (2011) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.258 · Cited by 4,641
Li, F., Duan, J., Tian, S., Ji, H., Zhu, Y., Wei, Z., & Zhao, D. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2019.122506 · Cited by 707
Trojanowicz, M., Bojanowska-Czajka, A., Bartosiewicz, I., & Kulisa, K. (2018) · Chemical Engineering Journal · doi:10.1016/j.cej.2017.10.153 · Cited by 550
Rayne, S., & Forest, K. (2009) · Journal of Environmental Science and Health, Part A · doi:10.1080/10934520903139811 · Cited by 475
Bioaccumulation of Perfluorinated Alkyl Acids: Observations and Models
Ng, C. A., & Hungerbühler, K. (2014) · Environmental Science & Technology · doi:10.1021/es404008g · Cited by 393
Metadata
- Authors
- Burns, D. C., Ellis, D. A., Li, H., McMurdo, C. J., & Webster, E.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-11-07
- Volume
- 42
- Issue
- 24
- Pages
- 9283-9288
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2015338499
- Cited by
- 270
- References
- 3
- FWCI
- 10.76
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Experimental p Ka Determination for Perfluorooctanoic Acid (PFOA) and the Potential Impact of p Ka Concentration Dependence on Laboratory-Measured Partitioning Phenomena and Environmental Modeling. https://app.cochat.ai/papers/10.1021/es802047v
- The paper
- Burns, D. C., Ellis, D. A., Li, H., McMurdo, C. J., & Webster, E. (2008). Experimental p Ka Determination for Perfluorooctanoic Acid (PFOA) and the Potential Impact of p Ka Concentration Dependence on Laboratory-Measured Partitioning Phenomena and Environmental Modeling. Environmental Science & Technology. https://doi.org/10.1021/es802047v
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
