The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.
Indoor Contamination with Hexabromocyclododecanes, Polybrominated Diphenyl Ethers, and Perfluoroalkyl Compounds: An Important Exposure Pathway for People?
Abstract
This review underlines the importance of indoor contamination as a pathway of human exposure to hexabromocyclododecanes (HBCDs), polybrominated diphenyl ethers (PBDEs), and perfluoroalkyl compounds (PFCs). There is ample evidence of substantial contamination of indoor dust with these chemicals and that their concentrations in indoor air exceed substantially those outdoors. Studies examining the relationship between body burden and exposure via indoor dust are inconsistent; while some indicate a link between body burdens and PBDE and HBCD exposure via dust ingestion, others find no correlation. Likewise, while concentrations in indoor dust and human tissues are both highly skewed, this does not necessarily imply causality. Evidence suggests exposure via dust ingestion is higher for toddlers than adults. Research priorities include identifying means of reducing indoor concentrations and indoor monitoring methods that provide the most "biologically-relevant" measures of exposure as well as monitoring a wider range of microenvironment categories. Other gaps include studies to improve understanding of the following: emission rates and mechanisms via which these contaminants migrate from products into indoor air and dust; relationships between indoor exposures and human body burdens; relevant physicochemical properties; the gastrointestinal uptake by humans of these chemicals from indoor dust; and human dust ingestion rates.
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Citations
Cites
An overview of brominated flame retardants in the environment
de Wit, C. A. (2002) · Chemosphere · doi:10.1016/s0045-6535(01)00225-9 · Cited by 2,811
Self-citationSources, fate and transport of perfluorocarboxylates
Prevedouros, K., Cousins, I. T., Buck, R. C., & Korzeniowski, S. H. (2006) · Environmental Science & Technology · doi:10.1021/es0512475 · Cited by 2,594
Brominated flame retardants: cause for concern?
Birnbaum, L. S., & Staskal, D. F. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.6559 · Cited by 1,702
Polybrominated Diphenyl Ethers in the Environment and in People: A Meta-Analysis of Concentrations
Hites, R. A. (2004) · Environmental Science & Technology · doi:10.1021/es035082g · Cited by 1,503
Peer Reviewed: Perfluorochemical Surfactants in the Environment
Giesy, J. P., & Kannan, K. (2002) · Environmental Science & Technology · doi:10.1021/es022253t · Cited by 1,100
Hexabromocyclododecanes (HBCDs) in the Environment and Humans: A Review
Covaci, A., Gerecke, A. C., Law, R. J., Voorspoels, S., Kohler, M., Heeb, N. V., Leslie, H., Allchin, C. R., & de Boer, J. (2006) · Environmental Science & Technology · doi:10.1021/es0602492 · Cited by 792
Self-citationDetection of Organophosphate Flame Retardants in Furniture Foam and U.S. House Dust
Stapleton, H. M., Klosterhaus, S., Eagle, S., Fuh, J., Meeker, J. D., Blum, A., & Webster, T. F. (2009) · Environmental Science & Technology · doi:10.1021/es9014019 · Cited by 766
Self-citationJones-Otazo, H. A., Clarke, J. P., Diamond, M. L., Archbold, J. A., Ferguson, G., Harner, T., Richardson, G. M., Ryan, J. J., & Wilford, B. (2005) · Environmental Science & Technology · doi:10.1021/es048267b · Cited by 651
Self-citationEndocrine disrupting chemicals in indoor and outdoor air
Rudel, R. A., & Perovich, L. J. (2009) · Atmospheric Environment · doi:10.1016/j.atmosenv.2008.09.025 · Cited by 546
Exposure of Americans to polybrominated diphenyl ethers
Lorber, M. (2008) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/sj.jes.7500572 · Cited by 531
Cited by
Sunderland, E. M., Hu, X. C., Dassuncao, C., Tokranov, A. K., Wagner, C. C., & Allen, J. G. (2019) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-018-0094-1 · Cited by 2,786
Risk to human health related to the presence of perfluoroalkyl substances in food
Panel), E. P. O. C. I. T. F. C. (. C., Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Grasl‐Kraupp, B., Hogstrand, C., Hoogenboom, L. (., Leblanc, J., et al. (2020) · EFSA Journal · doi:10.2903/j.efsa.2020.6223 · Cited by 989
Self-citationDe Silva, A. O., Armitage, J. M., Bruton, T. A., Dassuncao, C., Heiger-Bernays, W., Hu, X. C., Kärrman, A., Kelly, B., Ng, C., Robuck, A., et al. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4935 · Cited by 835
Self-citationFrye, C., Bo, E., Calamandrei, G., Calzà, L., Dessì‐Fulgheri, F., Fernández, M., Fusani, L., Kah, O., Kajta, M., Le Page, Y., et al. (2012) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02229.x · Cited by 431
Haug, L. S., Huber, S., Becher, G., & Thomsen, C. (2011) · Environment International · doi:10.1016/j.envint.2011.01.011 · Cited by 391
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Metadata
- Authors
- Harrad, S., de Wit, C. A., Abdallah, M. A.-E., Bergh, C., Björklund, J. A., Covaci, A., Darnerud, P. O., de Boer, J., Diamond, M., Huber, S., Leonards, P., Mandalakis, M., Östman, C., Haug, L. S., Thomsen, C., & Webster, T. F.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-04-13
- Volume
- 44
- Issue
- 9
- Pages
- 3221-3231
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2070968636
- Cited by
- 300
- References
- 75
- FWCI
- 21.67
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Indoor Contamination with Hexabromocyclododecanes, Polybrominated Diphenyl Ethers, and Perfluoroalkyl Compounds: An Important Exposure Pathway for People? https://app.cochat.ai/papers/10.1021/es903476t
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- Harrad, S., de Wit, C. A., Abdallah, M. A.-E., Bergh, C., Björklund, J. A., Covaci, A., Darnerud, P. O., de Boer, J., Diamond, M., Huber, S., Leonards, P., Mandalakis, M., Östman, C., Haug, L. S., Thomsen, C., & Webster, T. F. (2010). Indoor Contamination with Hexabromocyclododecanes, Polybrominated Diphenyl Ethers, and Perfluoroalkyl Compounds: An Important Exposure Pathway for People? Environmental Science & Technology. https://doi.org/10.1021/es903476t
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
