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Cited by 508

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Mass Transfer Limitation of Biotransformation: Quantifying Bioavailability

Open access
Bosma, Tom N. P., Middeldorp, Peter J. M., Schraa, Gosse, Zehnder, Alexander J. B.·1997·Environmental Science & Technology

Abstract

Biotransformation is controlled by the biochemical activity of microorganisms and the mass transfer of a chemical to the microorganisms. A generic mathematical concept for bioavailability is presented taking both factors into account. The combined effect of mass transfer of a substance to the cell and the intrinsic activity of the cell using the substance as primary substrate, is quantified in a bioavailability number ( Bn ). The concept can easily be extended to secondary substrates. The approach has been applied to explain the observed kinetics of the biotransformation of organic compounds in soil slurries and in percolation columns. The model allowed us to predict threshold concentrations below which no biotransformation is possible. Depending on the environmental system and the chemical involved, predicted threshold concentrations span a range of 11 orders of magnitude from nanograms to grams per liter and match with published experimental data. Mass transfer and not the intrinsic microbial activity is in most cases the critical factor in bioremediation.

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Crossref · 10.1021/es960383u

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Metadata

Authors
Bosma, T. N. P., Middeldorp, P. J. M., Schraa, G., & Zehnder, A. J. B.
Venue
Environmental Science & Technology
Published
1996-12-30
Volume
31
Issue
1
Pages
248-252
ISSN
  • 0013-936X (ISSN-L)
  • 1520-5851
OpenAlex
W2086100669
Cited by
508
References
18
FWCI
13.90
Type
journal article
Language
en
Open access
green

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.