The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A Synthetically Simple, Click-Generated Cyclam-Based Zinc(II) Sensor
Abstract
A cyclam-based macrocyclic sensor has been prepared using synthetically simple "click" chemistry to link a fluorophore to the macrocyclic receptor. This sensor shows high selectivity for Zn(II) over a range of other metals, providing a significant enhancement of fluorescence intensity over a wide pH range. As such, this is the first cyclam-based sensor demonstrated to be selective for Zn(II) and is the first example of a triazole being used as a coordinating ligand on an azamacrocycle. The sensor can access biologically available zinc in mammalian cells, sensing the Zn(II) flux that exists during apoptotic cell death.
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Citations
Cites
A genome-wide association study identifies novel risk loci for type 2 diabetes
Sladek, R., Rocheleau, G., Rung, J., Dina, C., Shen, L., Serre, D., Boutin, P., Vincent, D., Belisle, A., Hadjadj, S., et al. (2007) · Nature · doi:10.1038/nature05616 · Cited by 2,993
Zinc deficiency, DNA damage and cancer risk
Ho, E. (2004) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2004.07.005 · Cited by 518
Cited by
Banerjee, S., Veale, E. B., Phelan, C. M., Murphy, S. A., Tocci, G. M., Gillespie, L. J., Frimannsson, D. O., Kelly, J. M., & Gunnlaugsson, T. (2013) · Chemical Society Reviews · doi:10.1039/c2cs35467e · Cited by 688
Metal chelating systems synthesized using the copper(i) catalyzed azide-alkynecycloaddition
Struthers, H., Mindt, T. L., & Schibli, R. (2010) · Dalton Trans. · doi:10.1039/b912608b · Cited by 386
Metadata
- Authors
- Tamanini, E., Katewa, A., Sedger, L. M., Todd, M. H., & Watkinson, M.
- Venue
- Inorganic Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-12-03
- Volume
- 48
- Issue
- 1
- Pages
- 319-324
- ISSN
- 0020-1669 (ISSN-L)
- 1520-510X
- OpenAlex
- W2066379223
- Cited by
- 161
- References
- 2
- FWCI
- 5.98
- Type
- journal article
- Language
- en
- Open access
- closed
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