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Selected ion fragmentation with a tandem quadrupole mass spectrometer
Abstract
A tandem quadrupole mass spectrometer is used to create ion species from a sample, separate one individual ion species, fragment it, and obtain the mass spectrum of the fragments. Practicability of the Selected Ion Fragmentation Tandem Quadrupole Mass Spectrometer (SIFT QMS) is experimentally demonstrated. Normally large ion losses due to scattering in the collision-induced dissociation (CID) process are eliminated by performing CID in a 'RF-only' quadrupole. CID spectra with unit mass resolution are produced by the quadrupole mass filters. The CID spectrum of each component of a cyclohexane mixture containing three minor components is presented. Potential applications of SIFT QMS in mixture analysis and structure elucidation are discussed. (Author)
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Cited by
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Mass spectrometric determination of the amino acid sequence of peptides and proteins
Biemann, K., & Martin, S. A. (1987) · Mass Spectrometry Reviews · doi:10.1002/mas.1280060102 · Cited by 554
Vidova, V., & Spacil, Z. (2017) · Analytica Chimica Acta · doi:10.1016/j.aca.2017.01.059 · Cited by 352
Triple quadrupole mass spectrometry for direct mixture analysis and structure elucidation
Yost, R. A., & Enke, C. G. (1979) · Analytical Chemistry · doi:10.1021/ac50048a002 · Cited by 337
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Metadata
- Authors
- Yost, R. A., & Enke, C. G.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 1978-03
- Volume
- 100
- Issue
- 7
- Pages
- 2274-2275
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2034541601
- Cited by
- 359
- References
- 0
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- closed
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