The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Triple quadrupole mass spectrometry for direct mixture analysis and structure elucidation
Abstract
The triple quadrupole mass spectrometer is shown to be a simple and highly efficient system for the observation of the fragmentation pattern of selected ions. The instrument consists of, in series, a CI/EI ion source, a quadrupole mass filter, an RF-only quadrupole collision chamber, a second mass filter, and an electron multiplier. The high sensitivity of the MS/MS technique with quadrupoles depends particularly on the highly efficient low energy collision-induced dissociation process in the strong focusing RF quadrupole field. Detection limits for methane and nitrobenzene of 10 to the minus 15 mole are shown. Analysis of a mixture of six components, including two isomers and an isobaric compound is presented. Chemical noise is virtually eliminated by the selection of both parent and fragment ion. An application of the system for structure elucidation is also described. (Author)
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Cites
INTERPRETATION OF MASS SPECTRA
(1991) · Analytical Chemistry · doi:10.1021/ac00022a726 · Cited by 1,840
Selected ion fragmentation with a tandem quadrupole mass spectrometer
Yost, R. A., & Enke, C. G. (1978) · Journal of the American Chemical Society · doi:10.1021/ja00475a072 · Cited by 359
Self-citationLevsen, K., & Schwarz, H. (1976) · Angewandte Chemie International Edition in English · doi:10.1002/anie.197605091 · Cited by 242
Kondrat, R. W., McClusky, G. A., & Cooks, R. G. (1978) · Analytical Chemistry · doi:10.1021/ac50036a020 · Cited by 159
Mixture analysis by mass-analyzed ion kinetic energy spectrometry
Kruger, T. L., Litton, J. F., Kondrat, R. W., et al. (1976) · Analytical Chemistry · doi:10.1021/ac50008a016 · Cited by 135
McLafferty, F. W., & Bockhoff, F. M. (1978) · Analytical Chemistry · doi:10.1021/ac50023a021 · Cited by 116
Cited by
Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions
Picotti, P., & Aebersold, R. (2012) · Nature Methods · doi:10.1038/nmeth.2015 · Cited by 1,302
Targeted Proteomic Quantification on Quadrupole-Orbitrap Mass Spectrometer
Gallien, S., Duriez, E., Crone, C., Kellmann, M., Moehring, T., & Domon, B. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.o112.019802 · Cited by 510
Vidova, V., & Spacil, Z. (2017) · Analytica Chimica Acta · doi:10.1016/j.aca.2017.01.059 · Cited by 352
Parallel reaction monitoring using quadrupole‐Orbitrap mass spectrometer: Principle and applications
Bourmaud, A., Gallien, S., & Domon, B. (2016) · PROTEOMICS · doi:10.1002/pmic.201500543 · Cited by 308
Spellman, D. S., Wildsmith, K. R., Honigberg, L. A., Tuefferd, M., Baker, D., Raghavan, N., Nairn, A. C., Croteau, P., Schirm, M., Allard, R., et al. (2015) · PROTEOMICS – Clinical Applications · doi:10.1002/prca.201400178 · Cited by 161
Metadata
- Authors
- Yost, R. A., & Enke, C. G.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1979-10-01
- Volume
- 51
- Issue
- 12
- Pages
- 1251-1264
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W1998521509
- Cited by
- 337
- References
- 6
- FWCI
- 8.57
- Type
- journal article
- Language
- en
- Open access
- closed
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