Equilibrium and kinetics of glyconitrile formation in aqueous solution
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEquilibrium and kinetics of glyconitrile formation in aqueous solutionGordon. Schlesinger and Stanley L. MillerCite this: J. Am. Chem. Soc. 1973, 95, 11, 3729–3735Publication Date (Print):May 1, 1973Publication History Published online1 May 2002Published inissue 1 May 1973https://pubs.acs.org/doi/10.1021/ja00792a043https://doi.org/10.1021/ja00792a043research-articleACS PublicationsRequest reuse permissionsArticle Views600Altmetric-Citations78LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
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Merging formaldehyde and HCN into a productive chemistry that leads to both sugars and nucleobases under the same conditions is not obvious, because they react readily to yield glyconitrile in a fast and thermodynamically favoured process.
“The merging of their feedstock substrates, formaldehyde and HCN, into a productive chemistry that leads to both types of biological components under the same conditions is not obvious, mostly because they react readily to yield glyconitrile (8), in a process that is fast and thermodynamically favoured (Scheme 7, red transformations).95”
From The protometabolic nature of prebiotic chemistry (2023) · cites this paper as [95]
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- Authors
- Schlesinger, G., & Miller, S. L.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 1973-05
- Volume
- 95
- Issue
- 11
- Pages
- 3729-3735
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W3005321230
- Cited by
- 100
- References
- 0
- Citations by year
- 2025: 3 · 2024: 6 · 2023: 6 · 2022: 2 · 2021: 2 · 2020: 2 · 2019: 6 · 2018: 1 · 2017: 1 · 2015: 5 · 2014: 2 · 2013: 4 · 2012: 4
- FWCI
- 1.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Chemical Society (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Reaction Mechanisms
- Physical Sciences › Chemistry › Organic Chemistry › Carbohydrate Chemistry and Synthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Advanced Glycation End Products research
- Keywords
- aqueous solutions, chemical equilibrium, reaction kinetics, nitrile synthesis
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