The DOI matches its Crossref record.
Nanocoatings onto Arteries via Layer-by-Layer Deposition: Toward the in Vivo Repair of Damaged Blood Vessels
Abstract
The deposition of polysaccharide-based self-assembled nanocoatings onto damaged arteries is described as a means not only to protect a damaged artery against thrombogenesis, but also to control the healing processes by incorporating biologically active components within the multilayer. As shown by confocal microscopy, the polysaccharide multilayer was retained on the artery in physiological condition and prevented platelet adhesion. Diffusion of the polysaccharides within the artery was also observed and may be used to efficiently target the vascular wall. The NO-precursor l-arginine was used a drug model and incorporated within the self-assembled layers.
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Citations
Cited by
Technology-driven layer-by-layer assembly of nanofilms
Richardson, J. J., Björnmalm, M., & Caruso, F. (2015) · Science · doi:10.1126/science.aaa2491 · Cited by 1,641
Biomedical Applications of Layer‐by‐Layer Assembly: From Biomimetics to Tissue Engineering
Tang, Z., Wang, Y., Podsiadlo, P., & Kotov, N. A. (2006) · Advanced Materials · doi:10.1002/adma.200600113 · Cited by 1,302
Gao, S., Zhu, Y., Wang, J., Zhang, F., Li, J., & Jin, J. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201801944 · Cited by 334
Bioactive Coatings of Endovascular Stents Based on Polyelectrolyte Multilayers
Thierry, B., Winnik, F. M., Merhi, Y., Silver, J., & Tabrizian, M. (2003) · Biomacromolecules · doi:10.1021/bm0341834 · Cited by 321
Self-citationWood, K. C., Chuang, H. F., Batten, R. D., Lynn, D. M., & Hammond, P. T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602884103 · Cited by 270
Metadata
- Authors
- Thierry, B., Winnik, F. M., Merhi, Y., & Tabrizian, M.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-05-28
- Volume
- 125
- Issue
- 25
- Pages
- 7494-7495
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2061663215
- Cited by
- 184
- References
- 0
- FWCI
- 8.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Nanocoatings onto Arteries via Layer-by-Layer Deposition: Toward the in Vivo Repair of Damaged Blood Vessels. https://app.cochat.ai/papers/10.1021/ja034321x
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- Thierry, B., Winnik, F. M., Merhi, Y., & Tabrizian, M. (2003). Nanocoatings onto Arteries via Layer-by-Layer Deposition: Toward the in Vivo Repair of Damaged Blood Vessels. Journal of the American Chemical Society. https://doi.org/10.1021/ja034321x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
