The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Aptamers Switch on Fluorescence of Triphenylmethane Dyes
Abstract
MG and SRB aptamers, which are short RNA sequences originally selected only for binding to malachite green or sulforhodamine B, can greatly enhance the fluorescence of normally nonfluorescent triphenylmethane dyes. MG aptamer enhances the quantum yields of malachite green (MG) and a novel rigidized derivative, indolinyl malachite green (IMG) by >2000-fold. SRB aptamer brightens patent blue V and VF by >90-fold. These enhancements are specific because MG aptamer has no effect on patent blue dyes and SRB aptamer has little or no effect on MG and IMG. Such sequence-specific fluorescence labeling of short RNA motifs is a first step toward genetically encodable fusion tags for imaging selected RNAs in vitro and in cells.
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Cited by
Filonov, G. S., Moon, J. D., Svensen, N., & Jaffrey, S. R. (2014) · Journal of the American Chemical Society · doi:10.1021/ja508478x · Cited by 780
In Vitro Selection of Structure‐Switching Signaling Aptamers
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Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs
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Metadata
- Authors
- Babendure, J. R., Adams, S. R., & Tsien, R. Y.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-11-08
- Volume
- 125
- Issue
- 48
- Pages
- 14716-14717
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2052936390
- Cited by
- 494
- References
- 11
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- closed
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