The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Screening Mercury Levels in Fish with a Selective Fluorescent Chemosensor
Abstract
Societal concerns over toxic mercury accumulation in humans from fish and other dietary and environmental sources provide motivation to develop new tools and tactics for mercury detection in a wide range of laboratory and field settings. Here we report the synthesis, properties, and application of a selective and sensitive small-molecule chemosensor for fluorescence screening of mercury levels in fish. Mercuryfluor-1 (MF1) is a water-soluble, fluorescein-based reagent that features excellent selectivity for Hg2+ over competing analytes and the largest turn-on fluorescence response to date (>170-fold increase) for reporting this heavy metal ion in aqueous solution. Combining this chemoselective Hg2+ probe with a microwave digestion protocol provides a facile method for assaying mercury levels in fish samples with mercury concentrations spanning 0.1 to 8 ppm, a range well matched with the United States Environmental Protection Agency (U.S. EPA) standard for the maximum safe level of mercury in edible fish (0.55 ppm).
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Cites
Principles of Fluorescence Spectroscopy
Lakowicz, J. R. (1999) · Springer eBooks · doi:10.1007/978-1-4757-3061-6 · Cited by 26,947
Ecological effects, transport, and fate of mercury: a general review
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The toxicology of mercury—current exposures and clinical manifestations
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MS4, a seminaphthofluorescein-based chemosensor for the ratiometric detection of Hg(ii)
Nolan, E. M., & Lippard, S. J. (2005) · Journal of Materials Chemistry · doi:10.1039/b501615k · Cited by 106
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Metadata
- Authors
- Yoon, S., Albers, A. E., Wong, A. P., & Chang, C. J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-10-28
- Volume
- 127
- Issue
- 46
- Pages
- 16030-16031
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W1974930894
- Cited by
- 503
- References
- 8
- FWCI
- 12.43
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yoon, S., Albers, A. E., Wong, A. P., & Chang, C. J. (2005). Screening Mercury Levels in Fish with a Selective Fluorescent Chemosensor. Journal of the American Chemical Society. https://doi.org/10.1021/ja0557987
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