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Communicating Chemical Congregation: A Molecular AND Logic Gate with Three Chemical Inputs as a “Lab-on-a-Molecule” Prototype
Abstract
We demonstrate the first three-input molecular AND logic gate based on three chemical inputs as a direct way of detecting congregations of chemical species. The AND gate operates in water and responds to Na+, H+, and Zn2+ inputs with an enhanced fluorescence signal when pre-set concentration thresholds are exceeded. Future "lab-on-a-molecule" devices could have application in medicine for rapid disease screening.
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Citations
Cited by
de Silva, A. P., & Uchiyama, S. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.188 · Cited by 866
Self-citationDigital Information Processing in Molecular Systems
Szaciłowski, K. (2008) · Chemical Reviews · doi:10.1021/cr068403q · Cited by 827
Chemical Approaches to Molecular Logic Elements for Addition and Subtraction
Pischel, U. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200603990 · Cited by 447
Ozlem, S., & Akkaya, E. U. (2009) · Journal of the American Chemical Society · doi:10.1021/ja808389t · Cited by 372
All-photonic multifunctional molecular logic device
Andréasson, J., Pischel, U., Straight, S. D., Moore, T. A., Moore, A. L., & Gust, D. (2011) · Journal of the American Chemical Society · doi:10.1021/ja203456h · Cited by 350
Metadata
- Authors
- Magri, D. C., Brown, G. J., McClean, G. D., & de Silva, A. P.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-03-28
- Volume
- 128
- Issue
- 15
- Pages
- 4950-4951
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2034233659
- Cited by
- 336
- References
- 0
- FWCI
- 11.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- Magri, D. C., Brown, G. J., McClean, G. D., & de Silva, A. P. (2006). Communicating Chemical Congregation: A Molecular AND Logic Gate with Three Chemical Inputs as a “Lab-on-a-Molecule” Prototype. Journal of the American Chemical Society. https://doi.org/10.1021/ja058295%2B
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