The DOI matches its Crossref record.
Synthesis and Application of Quantum Dots FRET-Based Protease Sensors
Abstract
Preparation of FRET-based quantum dots as protease sensors-RGDC peptide molecules are bound to the surface of CdSe/ZnS quantum dots. The peptide molecules are then labeled with rhodamine dye molecules. The emission color of the quantum dots change from green to orange due to fluorescence resonance energy transfer (FRET) between the quantum dots and the bound rhodamine molecules. Cleavage of the peptide by selective proteases releases the rhodamine molecules from the quantum dots surface, which results in decreasing FRET efficiency between the quantum dots and the rhodamine molecules. The emission color of the quantum dots changes back to green.
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Citations
Cited by
Biomolecule-Based Nanomaterials and Nanostructures
Willner, I., & Willner, B. (2010) · Nano Letters · doi:10.1021/nl102083j · Cited by 290
Molecular imaging of the tumor microenvironment
Zhou, Z., & Lu, Z.-R. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.07.012 · Cited by 253
FRET Based Biosensor: Principle Applications Recent Advances and Challenges
Verma, A. K., Noumani, A., Yadav, A. K., & Solanki, P. R. (2023) · Diagnostics · doi:10.3390/diagnostics13081375 · Cited by 202
Metadata
- Authors
- Shi, L., De Paoli, V., Rosenzweig, N., & Rosenzweig, Z.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-07-26
- Volume
- 128
- Issue
- 32
- Pages
- 10378-10379
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W1998990083
- Cited by
- 352
- References
- 0
- FWCI
- 16.06
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Synthesis and Application of Quantum Dots FRET-Based Protease Sensors. https://app.cochat.ai/papers/10.1021/ja063509o
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- Shi, L., De Paoli, V., Rosenzweig, N., & Rosenzweig, Z. (2006). Synthesis and Application of Quantum Dots FRET-Based Protease Sensors. Journal of the American Chemical Society. https://doi.org/10.1021/ja063509o
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