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Ratiometric Temperature Sensing with Semiconducting Polymer Dots
Open accessAbstract
This communication describes ultrabright single-nanoparticle ratiometric temperature sensors based on semiconducting polymer dots (Pdots). We attached the temperature sensitive dye-Rhodamine B (RhB), whose emission intensity decreases with increasing temperature-within the matrix of Pdots. The as-prepared Pdot-RhB nanoparticle showed excellent temperature sensitivity and high brightness because it took advantage of the light harvesting and amplified energy transfer capability of Pdots. More importantly, the Pdot-RhB nanoparticle showed ratiometric temperature sensing under a single wavelength excitation and has a linear temperature sensing range that matches well with the physiologically relevant temperatures. We employed Pdot-RhB for measuring intracellular temperatures in a live-cell imaging mode. The exceptional brightness of Pdot-RhB allows this nanoscale temperature sensor to be used also as a fluorescent probe for cellular imaging.
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Cited by
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Huang, X., Song, J., Yung, B. C., Huang, X., Xiong, Y., & Chen, X. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00612h · Cited by 820
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Reisch, A., & Klymchenko, A. S. (2016) · Small · doi:10.1002/smll.201503396 · Cited by 634
Tunable Rigidity of (Polymeric Core)–(Lipid Shell) Nanoparticles for Regulated Cellular Uptake
Sun, J., Zhang, L., Wang, J., Feng, Q., Liu, D., Yin, Q., Xu, D., Wei, Y., Ding, B., Shi, X., et al. (2015) · Advanced Materials · doi:10.1002/adma.201404788 · Cited by 486
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Metadata
- Authors
- Ye, F., Wu, C., Jin, Y., Chan, Y.-H., Zhang, X., & Chiu, D. T.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-05-11
- Volume
- 133
- Issue
- 21
- Pages
- 8146-8149
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2146560584
- Cited by
- 390
- References
- 0
- FWCI
- 14.72
- Type
- journal article
- Language
- en
- Open access
- green
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- Ye, F., Wu, C., Jin, Y., Chan, Y.-H., Zhang, X., & Chiu, D. T. (2011). Ratiometric Temperature Sensing with Semiconducting Polymer Dots. Journal of the American Chemical Society. https://doi.org/10.1021/ja202945g
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