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Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones
Abstract
A catalytic amount of Hantzsch ester that could be regenerated in situ by Ru complexes under hydrogen gas has been employed in the biomimetic asymmetric hydrogenation of benzoxazinones with up to 99% ee in the presence of chiral phosphoric acid. The use of hydrogen gas as a reductant for the regeneration of Hantzsch esters makes this hydrogenation an ideal atom economic process.
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Cites
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Houtkooper, R. H., Cantó, C., Wanders, R. J., & Auwerx, J. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0026 · Cited by 899
Cited by
Parmar, D., Sugiono, E., Raja, S., & Rueping, M. (2014) · Chemical Reviews · doi:10.1021/cr5001496 · Cited by 2,118
Asymmetric Counteranion‐Directed Catalysis: Concept, Definition, and Applications
Mahlau, M., & List, B. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201205343 · Cited by 885
Combining transition metal catalysis and organocatalysis – an update
Du, Z., & Shao, Z. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35258c · Cited by 706
Asymmetrische Gegenanionen‐vermittelte Katalyse: Konzept, Definition und Anwendungen
Mahlau, M., & List, B. (2013) · Angewandte Chemie · doi:10.1002/ange.201205343 · Cited by 313
Metadata
- Authors
- Chen, Q.-A., Chen, M.-W., Yu, C.-B., Shi, L., Wang, D.-S., Yang, Y., & Zhou, Y.-G.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-09-23
- Volume
- 133
- Issue
- 41
- Pages
- 16432-16435
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2317800396
- Cited by
- 198
- References
- 1
- FWCI
- 14.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones. https://app.cochat.ai/papers/10.1021/ja208073w
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- Chen, Q.-A., Chen, M.-W., Yu, C.-B., Shi, L., Wang, D.-S., Yang, Y., & Zhou, Y.-G. (2011). Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones. Journal of the American Chemical Society. https://doi.org/10.1021/ja208073w
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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