The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Redox-Activated Manganese-Based MR Contrast Agent
Open accessAbstract
Here we report a simple Mn coordination complex with utility as a redox-sensitive MR probe. The HBET ligand stabilizes both the Mn(2+) and Mn(3+) oxidation states. In the presence of glutathione (GSH), low relaxivity Mn(III)-HBET is converted to high relaxivity Mn(II)-HBET with a 3-fold increase in relaxivity, and concomitant increase in MR signal. Alternately, hydrogen peroxide can convert Mn(II)-HBET to Mn(III)-HBET with a reduction in MR signal.
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Cites
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Brown, J. M., & Wilson, W. R. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1367 · Cited by 2,828
Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox
Rubartelli, A., & Lotze, M. T. (2007) · Trends in Immunology · doi:10.1016/j.it.2007.08.004 · Cited by 614
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Self-citationLanthanide Probes for Bioresponsive Imaging
Heffern, M. C., Matosziuk, L. M., & Meade, T. J. (2014) · Chemical Reviews · doi:10.1021/cr400477t · Cited by 1,202
Zhao, Z., Fan, H., Zhou, G., Bai, H., Liang, H., Wang, R., Zhang, X., & Tan, W. (2014) · Journal of the American Chemical Society · doi:10.1021/ja5029364 · Cited by 584
Cancer Treatment through Nanoparticle-Facilitated Fenton Reaction
Ranji-Burachaloo, H., Gurr, P. A., Dunstan, D. E., & Qiao, G. G. (2018) · ACS Nano · doi:10.1021/acsnano.8b07635 · Cited by 559
Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents
Ni, D., Bu, W., Ehlerding, E. B., Cai, W., & Shi, J. (2017) · Chemical Society Reviews · doi:10.1039/c7cs00316a · Cited by 484
Metadata
- Authors
- Loving, G. S., Mukherjee, S., & Caravan, P.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-03-19
- Volume
- 135
- Issue
- 12
- Pages
- 4620-4623
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2330939684
- Cited by
- 183
- References
- 2
- FWCI
- 7.40
- Type
- journal article
- Language
- en
- Open access
- green
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