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Intracellular Spatial Control of Fluorescent Magnetic Nanoparticles
Abstract
We report a facile intracellular manipulation of fluorescent magnetic Fe3O4-CdSe nanoparticles using magnetic force. The growth of CdSe quantum dots on Fe3O4 nanoparticles produces Fe3O4-CdSe nanoparticles with two distinct properties, fluorescence and superparamagnetism. After nonspecific surface modification using glutathione (GSH), the hydrophilic Fe3O4-CdSe@GSH nanoparticles can be easily uptaken by an HEK293T cell line. Confocal images indicate that the uptaken nanoparticles can be manipulated using a small magnet. The successful intracellular manipulation of magnetic nanoparticles may offer a new strategy for studying polarized cells.
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Citations
Cited by
Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications
Gao, J., Gu, H., & Xu, B. (2009) · Accounts of Chemical Research · doi:10.1021/ar9000026 · Cited by 1,907
Self-citationSynthesis and Optical Properties of Hybrid and Alloy Plasmonic Nanoparticles
Cortie, M. B., & McDonagh, A. M. (2011) · Chemical Reviews · doi:10.1021/cr1002529 · Cited by 834
Oh, J. K., & Park, J. M. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.08.005 · Cited by 427
New forms of superparamagnetic nanoparticles for biomedical applications
Xu, C., & Sun, S. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.008 · Cited by 349
Magnetic Nanostructures: Rational Design and Fabrication Strategies toward Diverse Applications
Wang, S., Xu, J., Li, W., Sun, S., Gao, S., & Hou, Y. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00370 · Cited by 129
Metadata
- Authors
- Gao, J., Zhang, W., Huang, P., Zhang, B., Zhang, X., & Xu, B.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-03-01
- Volume
- 130
- Issue
- 12
- Pages
- 3710-3711
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2061527531
- Cited by
- 240
- References
- 0
- FWCI
- 17.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gao, J., Zhang, W., Huang, P., Zhang, B., Zhang, X., & Xu, B. (2008). Intracellular Spatial Control of Fluorescent Magnetic Nanoparticles. Journal of the American Chemical Society. https://doi.org/10.1021/ja7103125
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