Cited by 349Characterization and Applications of Magnetic NanoparticlesNanoparticle-Based Drug DeliveryMagnetic Properties and Synthesis of Ferrites

New forms of superparamagnetic nanoparticles for biomedical applications

Xu, Chenjie, Sun, Shouheng·2013·Advanced Drug Delivery Reviews

Abstract

Magnetic nanoparticles (MNPs) based on iron oxide, especially magnetite (Fe3O4), have been explored as sensitive probes for magnetic resonance imaging and therapeutic applications. Such application potentials plus the need to achieve high efficiency and sensitivity have motivated the search for new forms of superparamagnetic NPs with additional chemical and physical functionalities. This review summarizes the latest development of high moment MNPs, multifunctional MNPs, and porous hollow MNPs for biosensing, molecular imaging, and drug delivery applications.

Integrity signals

Registry

Crossref · 10.1016/j.addr.2012.10.008

Cites

127 of 127 references verified0 citation errors · 0 not checkable

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  • Many iron oxide nanoparticles have been evaluated in preclinical and clinical trials, and several have reached the market.

    “Many iron oxide nanoparticles have been evaluated in preclinical and clinical trials, and several of them have reached the market (Table 1) [4, 22–26].”

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Authors
Xu, C., & Sun, S.
Affiliations
  • Nanyang Technological University (SG)
  • Brown University (US)
Corresponding author
  • Xu, Chenjie
  • Sun, Shouheng
Venue
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Published
2013-05
Volume
65
Issue
5
Pages
732-743
ISSN
0169-409X (ISSN-L)
OpenAlex
W2010177878
Cited by
349
References
128
Citations by year
2026: 5 · 2025: 13 · 2024: 17 · 2023: 23 · 2022: 14 · 2021: 27 · 2020: 35 · 2019: 22 · 2018: 41 · 2017: 34 · 2016: 37 · 2015: 38 · 2014: 30 · 2013: 11
FWCI
2.19
Type
journal article
Language
en
Open access
closed
Locations
  • Advanced Drug Delivery Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • DR-NTU (Nanyang Technological University) (submittedVersion)
Funders
Nanyang Technological University
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
  • Physical Sciences › Materials Science › Materials Chemistry › Magnetic Properties and Synthesis of Ferrites
Keywords
superparamagnetic nanoparticles, iron oxide nanoparticles, magnetite, multifunctional nanoparticles, MRI contrast agents, biosensing, molecular imaging, drug delivery, magnetic hyperthermia
MeSH terms
Animals, Humans, Drug Delivery Systems, Biomedical Technology, Molecular Imaging, Magnetite Nanoparticles

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