The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Enantioselective Synthesis of (+)-Cortistatin A, a Potent and Selective Inhibitor of Endothelial Cell Proliferation
Abstract
This manuscript describes an enantioselective synthesis of the naturally occurring inhibitor of endothelial cell proliferation, cortistatin A. Key steps of the synthesis are a silicate-directed elimination/ring expansion reaction and a highly diastereoselective aza-Prins cyclization with a subsequent transannular etherification.
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Citations
Cites
Transplacental Carcinogenesis by Stilbestrol
Folkman, J. (1971) · New England Journal of Medicine · doi:10.1056/nejm197108122850711 · Cited by 2,640
Cited by
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,866
Chemoselectivity: The Mother of Invention in Total Synthesis
Shenvi, R. A., O’Malley, D. P., & Baran, P. S. (2009) · Accounts of Chemical Research · doi:10.1021/ar800182r · Cited by 334
Metadata
- Authors
- Lee, H. M., Nieto-Oberhuber, C., & Shair, M. D.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-11-19
- Volume
- 130
- Issue
- 50
- Pages
- 16864-16866
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W1973500125
- Cited by
- 165
- References
- 1
- FWCI
- 7.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Lee, H. M., Nieto-Oberhuber, C., & Shair, M. D. (2008). Enantioselective Synthesis of (+)-Cortistatin A, a Potent and Selective Inhibitor of Endothelial Cell Proliferation. Journal of the American Chemical Society. https://doi.org/10.1021/ja8071918
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
