The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations
Abstract
A combination of NHC organocatalysis and transition-metal catalysis gives rise to fundamentally new cooperative reactivity and enables the regio- and enantioselective annulation reaction between enals and vinyl benzoxazinanones. The cooperative umpolung annulation eliminates mutual deactivation and leads to a diverse set of benzazepine derivatives in good yields with excellent enantioselectivities (up to 99% ee). The development of such a cooperative catalytic system dramatically expands the scope of NHC organocatalysis by opening up new metal-catalyzed reaction pathways for homoenolate intermediates.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
An overview of N-heterocyclic carbenes
Hopkinson, M. N., Richter, C., Schedler, M., & Glorius, F. (2014) · Nature · doi:10.1038/nature13384 · Cited by 4,264
Self-citationAsymmetric Transition Metal-Catalyzed Allylic Alkylations
Trost, B. M., & Vranken, D. L. V. (1996) · Chemical Reviews · doi:10.1021/cr9409804 · Cited by 3,205
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
Díez-González, S., Marion, N., & Nolan, S. P. (2009) · Chemical Reviews · doi:10.1021/cr900074m · Cited by 3,066
Organocatalysis by N-Heterocyclic Carbenes
Enders, D., Niemeier, O., & Henseler, A. (2007) · Chemical Reviews · doi:10.1021/cr068372z · Cited by 3,059
Asymmetric Transition-Metal-Catalyzed Allylic Alkylations: Applications in Total Synthesis
Trost, B. M., & Crawley, M. L. (2003) · Chemical Reviews · doi:10.1021/cr020027w · Cited by 2,845
Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes
Nicewicz, D. A., & MacMillan, D. W. C. (2008) · Science · doi:10.1126/science.1161976 · Cited by 2,489
Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes
Flanigan, D. M., Romanov-Michailidis, F., White, N. A., & Rovis, T. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00060 · Cited by 2,045
N‐Heterocyclic Carbenes as Organocatalysts
Marion, N., Díez‐González, S., & Nolan, S. P. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200603380 · Cited by 1,459
Organocatalytic umpolung: N-heterocyclic carbenes and beyond
Bugaut, X., & Glorius, F. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15333e · Cited by 1,394
Self-citationFortman, G. C., & Nolan, S. P. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15088j · Cited by 1,258
Metadata
- Authors
- Guo, C., Fleige, M., Janssen-Müller, D., Daniliuc, C. G., & Glorius, F.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-06-15
- Volume
- 138
- Issue
- 25
- Pages
- 7840-7843
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2412361205
- Cited by
- 344
- References
- 29
- FWCI
- 19.01
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations. https://app.cochat.ai/papers/10.1021/jacs.6b04364
- The paper
- Guo, C., Fleige, M., Janssen-Müller, D., Daniliuc, C. G., & Glorius, F. (2016). Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.6b04364
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
