Visualization of the Cellular Uptake and Trafficking of DNA Origami Nanostructures in Cancer Cells

Wang, Pengfei, Rahman, Mohammad Aminur, Zhao, Zhixiang, Weiss, Kristin, Zhang, Chao, Chen, Zhengjia, Hurwitz, Selwyn J., Chen, Zhuo G. +2 more·2018·Journal of the American Chemical Society

Cited by (269)

Items 201–269 of 269

  1. Functional nucleic acids for the treatment of diabetic complications
    Wen Wen, Yuzi Wei, Shaojingya Gao · 2023 · Nanoscale Advances
  2. Geometrically constrained cytoskeletal reorganisation modulates DNA nanostructures uptake
    Petra Elblová, Hana Andělová, Mariia Lunová, Judita Anthi, Skylar J.W. Henry, Xinyi Tu, Alexandr Dejneka, Milan Jirsa, Nicholas Stephanopoulos, Oleg Lunov · 2025 · Journal of Materials Chemistry B
  3. Framework nucleic acid-programmed aptamer–paclitaxel conjugates as targeted therapeutics for triple-negative breast cancer
    Lin Li, Pengyao Wei, Tong Kong, Bo Yuan, Pan Fu, Yong Li, Yuhui Wang, Jianping Zheng, Kaizhe Wang · 2025 · Nanoscale Horizons
  4. Extending the Capabilities of Molecular Force Sensors via DNA Nanotechnology
    Susana M. Beltrán, Marvin J. Slepian, Rebecca E. Taylor · 2020 · Critical Reviews in Biomedical Engineering
  5. Functionalization of Nucleic Acid Molecular Machines under Physiological Conditions: A Review
    Mo Zhou, Hongzhen Peng, Shihua Luo, Kai Jiao, Linjie Guo, Chunhai Fan, Jiang Li · 2025 · ACS Applied Bio Materials
  6. Noninvasive Framework Nucleic Acid Eye Drops for Retinal Administration
    Shitai Zhu, Qinglong Yan, Lihua Wang, Ying Zhu, Shihua Luo · 2023 · ACS Applied Bio Materials
  7. Precise construction of DNA origami‐based materials for functional regulation on biological interface
    Yushuai Wu, Xiaohui Wu, Run Tian, Yiming Wang, Baoquan Ding, Qiao Jiang · 2024 · Smart Molecules
  8. Diverse Chiral Nanotubes Assembled from Identical DNA Strands
    Chun Xie, Zhekun Chen, Kuiting Chen, Yingxin Hu, Fei Xu, Linqiang Pan · 2024 · Nano Letters
  9. DNA Nanodevices: From Mechanical Motions to Biomedical Applications
    Yiming Wang, Zhaoran Wang, Xiaohui Wu, Shaoli Liu, Fengsong Liu, Qiao Jiang, Baoquan Ding · 2021 · Current Topics in Medicinal Chemistry
  10. Autonomous and Programmable Reorganization of DNA‐Based Polymers Using Redox Chemistry**
    Serena Gentile, Erica Del Grosso, Leonard J. Prins, Francesco Ricci · 2023 · Chemistry - A European Journal
  11. Cellular Uptake of DNA Origami
    Maartje M. C. Bastings · 2023 · Methods in molecular biology
  12. Spatiotemporal Control over Polynucleotide Brush Growth on DNA Origami Nanostructures
    Yunqi Yang, Qinyi Lu, Yu Chen, Marcello DeLuca, Gaurav Arya, Yonggang Ke, Stefan Zauscher · 2023 · Angewandte Chemie International Edition
  13. Biomimetische DNA‐Nanoröhren: Gezielte Synthese und Anwendung nanoskopischer Kanäle
    Xiaoguo Liu, Yan Zhao, Pi Liu, Lihua Wang, Jianping Lin, Chunhai Fan · 2018 · Angewandte Chemie
  14. High Manganese Content of Lipid NanoMn (LNM) by Microfluidic Technology for Enhancing Anti-Tumor Immunity
    Jiawei Sun, Jingjing Gong, Lidong Gong, Chuanda Zhu, Longhao Li-Yang, Jingya Wang, Yuanyuan Yang, Shiming Zhang, Silu Liu, Jijun Fu et al. · 2024 · Pharmaceutics
  15. Functionalization of rod-shaped plant viruses for biomedical applications
    Wei Ning Qian, Zhuang Li, Jingyao Han, Ye Tian, Zhongwei Niu · 2025 · Nanoscale
  16. Membrane-targeted DNA frameworks with biodegradability recover cellular function and morphology from frozen cells
    Yedam Lee, Woo Hyuk Jung, Kyounghwa Jeon, Eui Bum Choi, Taeyoung Ryu, Chanseok Lee, Do‐Nyun Kim, Dong June Ahn · 2025 · Trends in biotechnology
  17. Heterochiral modifications enhance robustness and function of DNA in living human cells
    Tracy L. Mallette, Diane S. Lidke, Matthew R. Lakin · 2024 · ChemBioChem
  18. Poly‐Adenine‐Based Spherical Nucleic Acids for Efficient Live‐Cell MicroRNA Capture
    Kai Jiao, Qinglong Yan, Linjie Guo, Zhibei Qu, Shuting Cao, Xiaoliang Chen, Qian Li, Ying Jie Zhu, Jiang Li, Lihua Wang et al. · 2021 · Angewandte Chemie
  19. Applications of DNA-Functionalized Proteins
    Zhaoqiu Gong, Yuanyuan Tang, Ningning Ma, Wenhong Cao, Yong Wang, Shuang Wang, Ye Tian · 2021 · International Journal of Molecular Sciences
  20. Assessing the influence of small structural modifications in simple DNA-based nanostructures on their role as drug nanocarriers
    Alejandro Postigo, Pablo Martínez‐Vicente, Kevin N. Baumann, Jesús del Barrio, Silvia Hernández‐Ainsa · 2024 · Biomaterials Science
  21. Unraveling Framework Nucleic Acid–Skin Cell Interactions with a Co‐Culture System
    Christian Wiraja, Maria Esterlita Siantoputri, Sihan Liu, Ho Cheung Shum, Chenjie Xu · 2019 · Advanced Biosystems
  22. DNA‐Guided Programmable Protein Assemblies for Biomedical Applications
    Xuemei Xu, Da Han · 2021 · ChemPlusChem
  23. DNA nanodevices in nanomedicine and therapeutics
    Payal Vaswani, Hema Naveena A, Dhiraj Devidas Bhatia · 2022 · Elsevier eBooks
  24. Next-generation biomedical nanorobots: active design, intelligent control, and translational opportunities in regenerative and minimally invasive medicine
    Na Liu, Shi Tang, Shasha Yu, Yang Song, Haishan Zhang, Yizi Wang · 2026 · Journal of Nanobiotechnology
  25. Imaging of Nanoscale Gold in “Intact” Biological Cells by Environmental Electron Microscopy
    Domagoj Belić, Oihane Fragueiro, Dina Salah, Alison J. Beckett, Martin Volk, Mathias Brust · 2021 · The Journal of Physical Chemistry C
  26. Polymer‐DNA Carriers Co‐Deliver Photosensitizer and siRNA for Light‐Promoted Gene Transfection and Hypoxia‐Relieved Photodynamic Therapy
    Guiling Fan, Shengxin Hou, Wenkang Zhang, Hengfeng Jiang, Xiao Fan, Jiantao Yu, Leilei Tian · 2024 · Angewandte Chemie
  27. DNA Nanotags for Multiplexed Single-Particle Electron Microscopy and In Situ Electron Cryotomography
    Yuanfang Chen, Yiqian Huang, Yuhe Renee Yang · 2024 · JACS Au
  28. Tetrahedral DNA Nanostructure‐Modified Nanocoating for Improved Bioaffinity and Osseointegration of Titanium
    Chenghui Qian, Si Chen, Liman Chen, Chenyang Zhang, Lingyi Yang, Qiaowei Li, Binbin Kang, Xiaohong Chen, Peter Mei, Hongzhou Gu et al. · 2025 · Small
  29. Engineering a Floxuridine-integrated RNA Prism as Precise Nanomedicine for Drug Delivery
    Gaifang Pan, Yuan Ma, Jiao Zhang, Yuanyuan Guo, Fei Ding, Huan Ge, Qifeng Li, Xinyuan Zhu, Chuan Zhang · 2019 · Chemical Research in Chinese Universities
  30. Programming and monitoring surface-confined DNA computing
    Chenyun Sun, Mingqiang Li, Fei Wang · 2024 · Bioorganic Chemistry
  31. Bio-inspired Materials in Nanobiotechnology Applications and Industrial Potential Scale
    María del Pilar Rodríguez-Torres, Kaushik Pal · 2021 · Springer eBooks
  32. Binding of DNA origami to lipids: maximising yield and switching via strand-displacement
    Jasleen Kaur Daljit Singh, Esther Darley, Pietro Ridone, James P Gaston, Ali Abbas, Shelley F. J. Wickham, Matthew A. B. Baker · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  33. Ligand geometry dictates cellular and in vivo uptake of 3D DNA nanostructures
    Anjali Rajwar, Shravani RS, Payal Vaswani, Vinod Morya, Amlan Barai, Shamik Sen, Sharad Kumar Gupta, Mahendra S. Sonawane, Dhiraj Devidas Bhatia · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  34. Nanotechnology for Future Sustainable Plant Production Under Changing Environmental Conditions
    Ayesha Tahir, Jun Gu Kang, Jaffer Ali, Ameer Bibi, Shabbar Abbas · 2022 · Bioresource Technology
  35. Origami-Inspired Engineering: Math behind DONs
    Abdul Rafae Kamran · 2023 · VFAST Transactions on Mathematics
  36. NIR‐II Emissive Oligonucleotides Grafted π‐Conjugated Polymers for Low‐Temperature Photothermal and Gene Combined Therapy
    Guiling Fan, Shengxin Hou, Ying Gu, Hengfeng Jiang, Wenkang Zhang, WU Weitao, Mengying Wang, Leilei Tian · 2025 · Angewandte Chemie
  37. Programmable nucleic acid fibers: molecular weaving, dynamic functional engineering, and precision biomedical applications
    Xiaoxing Fang, Ji Zheng, Wenqi Gao, Zhenyi Liu, Xuewei Li, Chao Li, Tao Gao, Ruiping Zhang · 2025 · Coordination Chemistry Reviews
  38. Tetrahedral framework nucleic acid loaded celastrol ameliorates skin fibrosis by epithelial-mesenchymal transition prevention
    Junxin Cheng, Zhongyi Fang, Renzeng YANG, Yunfeng Lin, Sirong Shi · 2026 · Science China Materials
  39. Research on DNA Nanostructures Based on the Hybrid Chain Reaction for the Assignment Problem
    Risheng Wang, Zhixiang Yin, Jing Yang, Xinmu Yang, Zhen Tang · 2021 · Journal of Mathematics
  40. DNA origami assembled spheroid for evaluating cytotoxicity and infiltration of chimeric antigen receptor macrophage (CAR-M)
    Junhua Liu, Xiaofang He, Qingyao Zhu, Heming Wang, Xiaojiao Shan, Yicheng Zhao, Luo Zhang, Guangqi Song, Xiushan Yin · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  41. Rationally Designed DNA Assemblies for Biomedical Application
    Qiao Jiang, Qing Lin Liu, Zhaoran Wang, Baoquan Ding · 2020 · Springer eBooks
  42. DNA Origami Model for Simple Image Decoding
    Risheng Wang, Zhixiang Yin, Jianzhong Cui, Jing Yang, Zhen Tang, Xinmu Yang, Xianya Geng · 2020 · Discrete Dynamics in Nature and Society
  43. Programming Molecular Circuitry and Intracellular Computing with Framework Nucleic Acids
    Jiang Li, Chunhai Fan · 2021 · Wiley eBooks
  44. Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials
    Kirill A. Afonin · 2019 · MDPI eBooks
  45. Virus coated DNA nanostructures : a biological way for drug delivery
    Gaurav Singhai · 2021
  46. DNA Nanostructures for Cancer Diagnosis and Therapy
    Zhe Li, Yonggang Ke · 2022 · Wiley eBooks
  47. Sperm-like nanocarriers for ultrafast delivery of antisense DNA
    Xiaochen Tang, Tianshu Chen, Huinan Chen, Sinuo Yu, Siyu Cao, Chenbin Liu, Yonggeng Ma, Fenyong Sun, Qiuhui Pan, Xiaoli Zhu · 2022 · Nanoscale
  48. Deciphering plausible role of DNA nanostructures in drug delivery
    Anju Singh, Shoaib Khan, Nishu Nain, Shrikant Kukreti · 2023 · Elsevier eBooks
  49. Programmable nucleic acid nanostructures as platforms for bioresponsive contrast agents for MRI
    Y. Kristine · 2022
  50. Viral attachment blocking chimera composed of DNA origami and nanobody inhibits Pseudorabies Virus infection in vitro
    Swechchha Pradhan, Carter J. Swanson, Chloe Liliana Leff, Isadonna F. Tengganu, Melissa H. Bergeman, Ian B. Hogue, Rizal F. Hariadi · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Spatiotemporal Control over Polynucleotide Brush Growth on DNA Origami Nanostructures
    Yunqi Yang, Qinyi Lu, Yu Chen, Marcello DeLuca, Gaurav Arya, Yonggang Ke, Stefan Zauscher · 2023 · Angewandte Chemie
  52. Designer DNA Nanostructures and Their Cellular Uptake Behaviors
    Jing Ye, Donglei Yang, Chenzhi Shi, Fei Zhou, Pengfei Wang · 2024 · Wiley eBooks
  53. 3659 DNA nanotechnology for drug delivery
    Natalia Navarro, Carme Fàbrega, Ramón Eritja · 2025 · De Gruyter eBooks
  54. DNA Nanostructures Characterized via Dual Nanopore Resensing
    Wangwei Dong, Zezhou Liu, Ruiyao Liu, Deborah Kuchnir Fygenson, Walter Reisner · 2025 · ACS Nano
  55. Additional file 1 of NIR/pH-triggered aptamer-functionalized DNA origami nanovehicle for imaging-guided chemo-phototherapy
    Li, Mengyue, Yang, Geng, Zheng, Yue, Jiazhen Lv, Wanyi Zhou, Zhang, Hanxi, You, Fengming, Wu, Chunhui, Yang, Hong, Liu, Yiyao · 2023 · Figshare
  56. Evolutionary selection of DNA nanostructures for cellular uptake
    Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  57. DNA Nanostructures for siRNA Delivery
    Bharath Raj Madhanagopal, Sarah Youssef, Arun Richard Chandrasekaran · 2026 · Bioconjugate Chemistry
  58. Influence of Physicochemical Parameters on the in vitro Stability of DNA Tetrahedral Nanostructures
    Janvi Viroja, Kiransinh Narendrasinh Rajput, Sweny Jain, Dhiraj Devidas Bhatia · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Rational design of topology-defined DNA nanoframeworks for antigen delivery and cross-presentation
    Ying Cao, Yuanyuan Wu, Xian Huang, Kui Huang, Tomasz Maj, Zhao Xu, Jingwei Sun, Qian Shi, Yang Yang · 2026 · Journal of Nanobiotechnology
  60. Falafel-Style Wrapping of AuNPs for DNA Origami Barcodes
    Sarah Youssef, Thomas Swope, Thorsten L. Schmidt, Diana P. N. Gonçalves · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  61. From Blueprint to Breakthrough: How Far Can We Fold DNA Origami for Nano-Enabled Technologies?
    Amit K. Yadav, Damini Verma, Dhiraj Devidas Bhatia · 2026 · JACS Au
  62. Direct Cytosolic Delivery of Amphiphilic Framework Nucleic Acids for RNA Interference
    Lixuan Lin, Kai Jiao, Biancheng Wei, Fei Zhou, Yue Wang, Xia Liu, Zisheng Tang, Lihua Wang, Ying Zhu, Linjie Guo et al. · 2026 · Angewandte Chemie
  63. Direct Cytosolic Delivery of Amphiphilic Framework Nucleic Acids for RNA Interference
    Lixuan Lin, Kai Jiao, Biancheng Wei, Fei Zhou, Yue Wang, Xia Liu, Zisheng Tang, Lihua Wang, Ying Zhu, Linjie Guo et al. · 2026 · Angewandte Chemie International Edition
  64. Stabilizing DNA origami nanostructures for clinical translation through chemical and computational engineering
    Melina Sarabandi, Vinit Kumar, Abazar Ghorbani, Carme Fàbrega, Natalia Navarro, Ramón Eritja, Moxian Chen · 2026 · Advanced Sensor and Energy Materials
  65. Iterative Selection of DNA Nanostructures for Cellular Uptake
    Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson · 2026 · Advanced Materials
  66. DNA Framework Nanomachines for Translational Medicine
    Lixuan Lin, Kai Jiao, Linjie Guo, Chunhai Fan, Jiang Li · 2026 · Accounts of Materials Research
  67. Cellular and In Vivo Fate of DNA Nanostructures
    Jungang Ren, Qian Wu, Luke P. Lee, Zhenbao Liu · 2026 · ACS Applied Materials & Interfaces
  68. DNA Origami Uptake in Y‐79 Retinoblastoma Cells Driven by Oligolysine Coating
    Anna Klose, Zahra Gounani, Sergei V. Raik, Artturi Koivuniemi, Sonja Korhonen, Mika Reinisalo, Tatu Lajunen, Veikko Linko, Timo Laaksonen · 2026 · Small Structures
  69. DNA Nanostructures for Overcoming Cancer Drug Resistance: Mechanisms, Therapeutic Strategies, and Translational Challenges
    Botao Liu, Chenxin Liu, Jiale Liang, Bo Huang, Lan Yao, Yun Wang, Yunfeng Lin · 2026 · Small