The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Free Radical Studies of Ellagic Acid, a Natural Phenolic Antioxidant
Abstract
Ellagic acid, a plant-derived polyphenol, inhibits gamma-radiation (hydroxyl radical) induced lipid peroxidation in rat liver microsomes in a dose- and concentration-dependent manner. Its antioxidant capacity has been estimated using the 1,1-diphenyl-2-picrylhydrazyl radical assay. To understand the actual mechanisms involved in antioxidant activity and the free radical scavenging ability,a nanosecond pulse radiolysis technique has been employed. The rate constants for the reactions of several reactive oxygen species and reactive nitrogen species such as hydroxyl, peroxyl, and nitrogen dioxide radicals have been found to be in the range of 10(6)-10(9) M(-1) s(-1). The ellagic acid radicals have been characterized by the absorption spectra and decay kinetics. Studies on the reactions of ellagic acid with the 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) radical and the radicals of ellagic acid with ascorbate have been used to estimate its one-electron reduction potential. Ellagic acid has also been found to be a good scavenger of peroxynitrite. Using stopped-flow reaction analyzer with absorption detection, the rate constant for this reaction has been determined to be 3.7 x 10(3) M(-1) s (-1). The electron spin resonance spectra of the oxidized ellagic acid radicals have been recorded by horseradish peroxidase and hydrogen peroxide method.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
Free radicals in biology and medicine
(1991) · General Pharmacology: The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Buxton, G. V., Greenstock, C. L., Helman, W. P., & Ross, A. B. (1988) · Journal of Physical and Chemical Reference Data · doi:10.1063/1.555805 · Cited by 12,332
Zafrilla, P., Ferreres, F., & Tomás-Barberán, F. A. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010192x · Cited by 314
Scott, S. L., Chen, W. J., Bakac, A., & Espenson, J. H. (1993) · The Journal of Physical Chemistry · doi:10.1021/j100127a022 · Cited by 306
Narayanan, B. A., Geoffroy, O., Willingham, M. C., Re, G. G., & Nixon, D. W. (1999) · Cancer Letters · doi:10.1016/s0304-3835(98)00323-1 · Cited by 283
Inhibitory effects of phenolic compounds on CCl4-induced microsomal lipid peroxidation
Cholbi, M. R., Paya, M., & Alcaraz, M. J. (1991) · Experientia · doi:10.1007/bf01945426 · Cited by 264
Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice
Khanduja, K. L., Gandhi, R. K., Pathania, V, & Syal, N. (1999) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(99)00021-6 · Cited by 191
Peroxynitrite: A two-faced metabolite of nitric oxide
Muijsers, R. B. R., Folkerts, G., Henricks, P. A. J., Sadeghi-Hashjin, G., & Nijkamp, F. P. (1997) · Life Sciences · doi:10.1016/s0024-3205(96)00651-0 · Cited by 176
Phenolic Constituents, Furans, and Total Antioxidant Status of Distilled Spirits
Goldberg, D. M., Hoffman, B., Yang, J., & Soleas, G. J. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9811626 · Cited by 170
Cited by
The role of stroma in pancreatic cancer: Diagnostic and therapeutic implications
Erkan, M., Hausmann, S., Michalski, C. W., Fingerle, A. A., Dobritz, M., Kleeff, J., & Friess, H. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.115 · Cited by 662
Rudrapal, M., Rakshit, G., Singh, R. P., Garse, S., Khan, J., & Chakraborty, S. (2024) · Antioxidants · doi:10.3390/antiox13040429 · Cited by 259
Mangiferin, a natural polyphenol protects the hepatic damage in mice caused by CCl4 intoxication
Rasool, M., Sabina, E. P., Mahinda, P. S., & Gnanaselvi, B. C. (2012) · Comparative Clinical Pathology · doi:10.1007/s00580-011-1190-y · Cited by 10
Metadata
- Authors
- Priyadarsini, K. I., Khopde, S. M., Kumar, S. S., & Mohan, H.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-02-26
- Volume
- 50
- Issue
- 7
- Pages
- 2200-2206
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2013194529
- Cited by
- 356
- References
- 17
- FWCI
- 3.42
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Free Radical Studies of Ellagic Acid, a Natural Phenolic Antioxidant. https://app.cochat.ai/papers/10.1021/jf011275g
- The paper
- Priyadarsini, K. I., Khopde, S. M., Kumar, S. S., & Mohan, H. (2002). Free Radical Studies of Ellagic Acid, a Natural Phenolic Antioxidant. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf011275g
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
