The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Antioxidative Properties of Tripeptide Libraries Prepared by the Combinatorial Chemistry
Abstract
Two series of combinatorial tripeptide libraries were constructed, based on an antioxidative peptide isolated from a soybean protein hydrolysate. One was a library of 108 peptides containing either His or Tyr residues. Another was a library of 114 peptides related to Pro-His-His, which had been identified as an active core of the antioxidative peptide. The antioxidative properties of these libraries were examined by several methods, such as the antioxidative activity against the peroxidation of linoleic acid, the reducing activity, the radical scavenging activity, and the peroxynitrite scavenging activity. Two Tyr-containg tripeptides showed higher activities than those of two His-containing tripeptides in the peroxidation of linoleic acid. Tyr-His-Tyr showed a strong synergistic effects with phenolic antioxidants. However, the tripeptide had only marginal reducing activity and a moderate peroxynitrite scavenging activity. Cysteine-containing tripeptides showed the strong peroxynitrite scavenging activity. Change of either the N-terminus or C-terminus of Pro-His-His to other amino acid residues did not significantly alter their antioxidative activity. Tripeptides containing Trp or Tyr residues at the C-terminus had strong radical scavenging activities, but very weak peroxynitrite scavenging activity. The present results allow us to understand why protein digests have such a variety of antioxidative properties.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Miller, N. J., Rice-Evans, C., Davies, M. J., Gopinathan, V., & Milner, A. (1993) · Clinical Science · doi:10.1042/cs0840407 · Cited by 3,105
Stadtman, E. R. (1993) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.62.070193.004053 · Cited by 1,395
Generation and propagation of radical reactions on proteins
Hawkins, C. L., & Davies, M. J. (2001) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00252-8 · Cited by 751
Antioxidative Action of Indole Compounds during the Autoxidation of Linoleic Acid
Mitsuda, H., Yasumoto, K., & Iwami, K. (1966) · Eiyo To Shokuryo · doi:10.4327/jsnfs1949.19.210 · Cited by 573
[24] Nitric oxide assay using hemoglobin method
Murphy, M. E., & Noack, E. (1994) · Methods in Enzymology · doi:10.1016/s0076-6879(94)33027-1 · Cited by 360
The effect of some amino acids on the oxidation of linoleic acid and its methyl ester
Marcuse, R. (1962) · Journal of the American Oil Chemists Society · doi:10.1007/bf02631680 · Cited by 147
Antioxidative Peptide from Milk Fermented with Lactobacillus delbrueckii subsp. bulgaricus IFO13953.
KUDOH, Y., MATSUDA, S., Igoshi, K., & Oki, T. (2001) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.48.44 · Cited by 119
Autoxidation of Methyl Linoleate in Freeze‐Dried Model Systems. III. Effects of Added Amino Acids
Karel, M., Tannenbaum, S. R., WALLACE, D. H., & MALONEY, H. (1966) · Journal of Food Science · doi:10.1111/j.1365-2621.1966.tb03266.x · Cited by 92
Antioxidant activity of protein hydrolyzates from aquatic species
Shahidi, F., & Amarowicz, R. (1996) · Journal of the American Oil Chemists Society · doi:10.1007/bf02523384 · Cited by 82
Antioxidative Activity of Peptides Prepared by Enzymatic Hydrolysis of Egg-white Albumin.
Tsuge, N., EIKAWA, Y., Nomura, Y., Yamamoto, M., & Sugisawa, K. (1991) · Nippon Nōgeikagaku Kaishi · doi:10.1271/nogeikagaku1924.65.1635 · Cited by 82
Cited by
A Comprehensive Review on Lipid Oxidation in Meat and Meat Products
Domínguez, R., Pateiro, M., Gagaoua, M., Barba, F. J., Zhang, W., & Lorenzo, J. M. (2019) · Antioxidants · doi:10.3390/antiox8100429 · Cited by 1,926
Sánchez, A., & Vázquez, A. (2017) · Food Quality and Safety · doi:10.1093/fqs/fyx006 · Cited by 868
Antioxidant activity of peptides derived from egg white proteins by enzymatic hydrolysis
Dávalos, A., Miguel, M., Bartolomé, B., & López-Fandiño, R. (2004) · Journal of Food Protection · doi:10.4315/0362-028x-67.9.1939 · Cited by 495
Novel antioxidants in food quality preservation and health promotion
Shahidi, F., & Zhong, Y. (2010) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201000044 · Cited by 479
Antioxidant Activity of Zein Hydrolysates in a Liposome System and the Possible Mode of Action
Kong, B., & Xiong, Y. L. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf060632q · Cited by 387
Metadata
- Authors
- Saito, K., Jin, D.-H., Ogawa, T., Muramoto, K., Hatakeyama, E., Yasuhara, T., & Nokihara, K.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-05-10
- Volume
- 51
- Issue
- 12
- Pages
- 3668-3674
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W1981667724
- Cited by
- 386
- References
- 13
- FWCI
- 1.50
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antioxidative Properties of Tripeptide Libraries Prepared by the Combinatorial Chemistry. https://app.cochat.ai/papers/10.1021/jf021191n
- The paper
- Saito, K., Jin, D.-H., Ogawa, T., Muramoto, K., Hatakeyama, E., Yasuhara, T., & Nokihara, K. (2003). Antioxidative Properties of Tripeptide Libraries Prepared by the Combinatorial Chemistry. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf021191n
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
